199 citations
,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
99 citations
,
October 2008 in “Journal of Investigative Dermatology” This study identified genetic mutations linked to congenital ichthyosis in families from the UAE and Turkey, revealing a connection between keratinization disorders and impaired filaggrin processing.
74 citations
,
October 2015 in “Experimental Dermatology” This study found that mTOR gene expression was significantly increased and S6K1 activation was observed in skin samples from acne patients compared to healthy controls, suggesting mTORC1's involvement in acne pathogenesis.
70 citations
,
April 2017 in “Lasers in surgery and medicine” This study found that blue light at a wavelength of 453 nm promoted hair growth ex vivo, potentially through interacting with OPN3 receptors in human hair follicles.
46 citations
,
August 2022 in “Journal of Endocrinological Investigation” In this study, the authors concluded that COVID-19 may not cause direct long-term harm to testicular function, but temporary indirect effects could occur, suggesting a possible delay in pursuing parenthood post-recovery.
18 citations
,
March 2014 in “Drug Development and Industrial Pharmacy” This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.
15 citations
,
January 2023 in “Antioxidants” This review discusses oxidative stress in alopecia areata pathogenesis and potential treatment strategies, reporting no new clinical results but suggesting biomarkers for oxidative stress and discussing JAK inhibitors as promising options.
15 citations
,
October 2003 in “Annals of Oncology” Hair loss can occur as a side effect of certain breast cancer treatments, but minoxidil can help regrow hair.
14 citations
,
January 2017 in “Elsevier eBooks” This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.
14 citations
,
December 2016 in “Sexual Medicine” This study identified differences in adverse symptoms among patients with post-finasteride syndrome based on short and long androgen receptor gene polymorphisms.
11 citations
,
October 2021 in “Orphanet journal of rare diseases” This study found that patients with RASopathies have lower serum IgA and CD8 levels compared to controls, indicating a potential risk for developing autoimmune disorders.
11 citations
,
October 2011 in “Allergologia et immunopathologia” A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.
8 citations
,
November 2019 in “International Journal of Morphology” This study found that using henna dye positively affected hair cuticula pattern and diameters compared to undyed hair, though the degree of change may vary based on hair phenotype and condition prior to treatment.
7 citations
,
June 2022 in “Biology” In this study, researchers observed that male COVID-19 patients with more than 23 CAG repeats in the androgen receptor gene and lower testosterone levels experienced more severe disease outcomes.
6 citations
,
April 2021 in “NAR Genomics and Bioinformatics” This study found extensive co-evolution of polyglutamine repeat lengths in neural protein clusters, highlighting their potential role in neurocognitive variation and neuropsychiatric disease development.
5 citations
,
January 2021 in “Dermatology Online Journal” This case report describes erosive pustular dermatosis of the scalp in a patient undergoing gefitinib treatment for lung cancer, and reviews literature on drug-induced cases of this rare condition.
4 citations
,
July 2024 in “Radiotherapy and Oncology” This study highlights that variations in clinical outcome reporting can undermine the validation of NTCP models for RIA, stressing the need for a standardized and objective scoring system.
4 citations
,
May 2024 in “Rapid Communications in Mass Spectrometry” This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.
4 citations
,
September 2013 in “Journal of Plastic Surgery and Hand Surgery” This study details the successfully treated case of a 16-year-old girl with congenital alopecia due to encephalocraniocutaneous lipomatosis, resulting in high patient satisfaction after hair restoration.
3 citations
,
June 2025 in “Biomedicines” This review discusses the potential link between gut microbiota alterations and the onset and progression of alopecia areata, identifying it as a possible pathogenetic factor and therapeutic target, but reports no new clinical results.
3 citations
,
May 2025 in “Archives of Gynecology and Obstetrics” In this study, researchers reported that women with polycystic ovary syndrome in a German-speaking population had higher probabilities of depression, anxiety, sleep disorders, and obstructive sleep apnea, all associated with BMI and insulin resistance.
3 citations
,
July 2023 in “Cells” This study found that topical application of recombinant human MG53 protein mitigated nitrogen mustard-induced skin injuries in mice by preserving epidermal integrity and hair follicle structure.
3 citations
,
March 2021 in “JAAD case reports” This case report describes a 40-year-old man whose vitiligo and psoriasis responded favorably to ixekizumab after experiencing vitiligo onset and psoriasis relapse during adalimumab treatment.
3 citations
,
June 2019 in “Dermatologic Therapy” This study reported that the Biofibre® hair implantation system, used on 1,518 patients with various degrees of baldness and causes of alopecia, delivered immediate and visible results without scarring or hospitalization, which greatly improved patients' self-esteem and psychological well-being.
2 citations
,
July 2025 in “RMD Open” This study found that IL-1 blockers are effective for SURF and identified predictors of colchicine resistance, emphasizing the need for refined diagnostic criteria and personalized treatment due to the heterogeneity observed within SURF.
2 citations
,
May 2024 in “Nanomaterials” This study reports the synthesis of a hectorite/phenanthroline nanomaterial which acts as a potential fluorescent sensor for detecting Zn ions in water, offering a solution to the low solubility issue of traditional metal ion-detecting molecules.
2 citations
,
April 2024 in “Dermatology Practical & Conceptual” This study emphasizes the importance of regular dental check-ups for patients undergoing systemic treatments for psoriatic disease, as it helps prevent oral complications associated with these medications. It recommends collaboration between dermatologists and oral health specialists to effectively manage and communicate these risks.
2 citations
,
February 2021 in “Endocrinology, diabetes & metabolism case reports” This case report describes a 15-year-old girl with severe hyperandrogenaemia linked to both an ovarian androgen-secreting tumor and HAIR-AN syndrome, highlighting the complexity of diagnosing polycystic ovarian syndrome.
1 citations
,
March 2026 in “American Journal of Clinical Dermatology” In this Italian retrospective study, ritlecitinib 50 mg/day showed effectiveness and good tolerability for treating severe alopecia areata over 24 weeks, achieving significant hair regrowth particularly in adolescents, as well as improvements in eyebrows, eyelashes, nails, and quality of life, with mostly mild adverse effects.
1 citations
,
July 2025 in “PubMed” This pilot study found that cord blood platelet-rich plasma treatment was safe and improved symptoms and sexual function in women with vulvar lichen sclerosus after standard topical corticosteroid treatment.