COVID-19 Severity and Androgen Receptor Polymorphism

June 2022 in “ Biology ”

Alessandra Buonacquisto, Anna Chiara Conflitti, Francesco Pallotti, Antonella Anzuini, Serena Bianchini, Luisa Caponecchia, Anna Carraro, Maria Rosa Ciardi, Fabiana Faja, Cristina Fiori, Daniele Gianfrilli, Andrea Lenzi, Miriam Lichtner, Claudio Maria Mastroianni, Patrizia Pasculli, Flavio Rizzo, Paola Salacone, A. Sebastianelli, Francesco Lombardo, Donatella Paoli

androgen receptor CAG polymorphism testosterone androgenic signaling

Studysummary In this study, researchers observed that male COVID-19 patients with more than 23 CAG repeats in the androgen receptor gene and lower testosterone levels experienced more severe disease outcomes.

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