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GlossaryCAG Repeats (CAG Repeat Polymorphism)

repeated DNA sequences of cytosine, adenine, and guanine

CAG repeats refer to sequences of three DNA nucleotides—cytosine, adenine, and guanine—that are repeated multiple times in a row within a gene. These repeats can expand abnormally in certain genetic disorders, such as Huntington's disease, leading to the production of malfunctioning proteins and subsequent cellular damage.

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A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

research A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

16 citations, December 2014 in “International Journal of Biological Markers”

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

14 citations, December 2016 in “Sexual Medicine”

Finasteride side effects in young men may be linked to specific gene variations.

research CAG Polymorphism in the Androgen Receptor Gene in Women May Be Associated with Nodulocystic Acne

7 citations, January 2019 in “Postepy Dermatologii I Alergologii”

Certain gene variations might be linked to severe acne in women but not in men.

research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?

29 citations, July 2013 in “The Journal of Sexual Medicine”

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

research Polymorphism of CAG and GGN Repeats of Androgen Receptor Gene in Women with Polycystic Ovary Syndrome

9 citations, September 2015 in “Reproductive Biomedicine Online”

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 450 upvotes 4 months ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community 3 months 5g Min only before/after, 26 y/o

in Is this regrowth? 454 upvotes 1 week ago

The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 30 upvotes 3 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community Why do I have the feeling that this subreddit is flooded by Kintor employees?

in Chat 132 upvotes 4 months ago

Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.

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