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GlossaryCAG Repeats (CAG Repeat Polymorphism)

repeated DNA sequences of cytosine, adenine, and guanine

CAG repeats refer to sequences of three DNA nucleotides—cytosine, adenine, and guanine—that are repeated multiple times in a row within a gene. These repeats can expand abnormally in certain genetic disorders, such as Huntington's disease, leading to the production of malfunctioning proteins and subsequent cellular damage.

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A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

research A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

16 citations , December 2014 in “International Journal of Biological Markers”

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

14 citations , December 2016 in “Sexual Medicine”

Finasteride side effects in young men may be linked to specific gene variations.

research CAG Polymorphism in the Androgen Receptor Gene in Women May Be Associated with Nodulocystic Acne

7 citations , January 2019 in “Postepy Dermatologii I Alergologii”

Certain gene variations might be linked to severe acne in women but not in men.

research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?

29 citations , July 2013 in “The Journal of Sexual Medicine”

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

research Polymorphism of CAG and GGN Repeats of Androgen Receptor Gene in Women with Polycystic Ovary Syndrome

9 citations , September 2015 in “Reproductive Biomedicine Online”

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 6 months ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 451 upvotes 1 year ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community 3 months 5g Min only before/after, 26 y/o

in Is this regrowth? 451 upvotes 9 months ago

The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 10 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

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