9 citations
,
July 2017 in “Dermatologic Therapy” Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
20 citations
,
June 2011 in “ISRN Dermatology (Print)” This case report describes a woman experiencing severe hair loss due to allergic contact dermatitis from a hair dye containing PPD.
51 citations
,
January 1989 in “Journal of Investigative Dermatology” This study found that sebaceous glands in bald scalp have greater androgen binding affinity and capacity than those in hairy scalp, possibly contributing to the androgenic response seen in male pattern baldness.
42 citations
,
January 2008 in “Dermatology” This study reports that dermoscopy is a useful diagnostic tool for distinguishing acute diffuse and total alopecia of the female scalp from female pattern hair loss by identifying specific hair features.
30 citations
,
September 2004 in “Experimental Dermatology” This study found that minoxidil did not significantly increase hair shaft elongation in ex vivo human hair follicle culture, questioning the suitability of this method for studying its hair-growth-promoting effects.
18 citations
,
July 2018 in “Skin appendage disorders” This review discusses trichoscopic features of hair disorders in individuals with dark skin phototypes and reports no new clinical results; the authors emphasize the need for more specific diagnostic criteria for these populations.
10 citations
,
January 2012 in “Journal of biomedical optics” This study used ultrahigh-resolution optical coherence tomography to observe hair shaft structures, finding melanin granules absent only in white hair, which may explain color differences between black and white hair.
5 citations
,
July 2020 in “Journal of Cosmetic Dermatology” This study found that using a vibration anesthetic device during scalp mesotherapy significantly reduced pain in patients with androgenetic alopecia and alopecia areata compared to the non-vibration side.
4 citations
,
May 2019 in “Skin Research and Technology” This study found that male pattern hair loss worsened significantly after stopping finasteride, revealing a "rebound effect" where terminal hair transformed into miniaturized hair over 30 months off the drug.
234 citations
,
December 1996 in “Journal of The American Academy of Dermatology” The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.
118 citations
,
May 2015 in “European journal of pharmaceutics and biopharmaceutics” This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.
12 citations
,
January 2008 in “Drugs” This review critically assesses current topical therapies for scalp psoriasis and reports no new clinical results; the authors highlight the need for controlled trials to evaluate treatment efficacy.
11 citations
,
November 2015 in “Skin Research and Technology” This study found that individuals with patterned hair loss, both male and female, showed a slower linear hair growth rate compared to controls with hair of equal thickness.
10 citations
,
January 2007 in “Dermatology” This study reported higher levels of certain proteins, such as DAX-1, SRY, and WT-1, in the bald scalp of patients with androgenetic alopecia.
6 citations
,
December 2014 in “Clinical and Experimental Dermatology” In this study, hair density and thickness in nonbalding scalp areas varied with the severity and BASP subtypes of androgenetic alopecia in East Asian men, showing notable decreases in some subtypes.
2 citations
,
October 2023 in “Dermatology practical & conceptual” This systematic review evaluated 60 studies on trichoscopy in hair and scalp disorders, revealing gaps in accounting for variables like disease stage or hair texture, and underscoring a need for more comprehensive analyses to fully understand trichoscopic patterns.
March 2026 in “Open MIND” Early treatment of scalp infections can prevent permanent hair loss.
October 2024 in “TURKDERM” Hair transplantation can lead to rare scalp complications, requiring careful follow-up and treatment.
August 2016 in “Journal of Investigative Dermatology” This study found that Rosebay extract significantly reduced dandruff and sebum production, suggesting it may be an effective anti-dandruff ingredient as a complement or alternative to antifungal treatments.
5 citations
,
October 1988 in “Clinics in Dermatology” This article reviews various types of alopecia, their diagnostic features, and patterns, but presents no new clinical findings; the authors discuss multiple mechanisms and classification challenges.
June 2023 in “International journal of pharmaceutical quality assurance” This study found that videodermoscopy is a promising non-invasive tool for distinguishing between types of non-scarring alopecia on the scalp, highlighting its potential in dermatological practice.
7 citations
,
November 2011 in “Skin Research and Technology” The authors observed that the patterned melanoderma on the hairless scalp of fair-skinned Caucasian men with androgenic alopecia resembled similar patterns seen on facial skin.
4 citations
,
November 2020 in “BMC Dermatology” This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.
1 citations
,
May 2023 in “Frontiers in medicine” This review explores how hair dyes and perms can damage hair structure and notes that while some adverse outcomes like skin irritation and allergic reactions have been reported, evidence from human studies remains inconsistent regarding potential risks, including cancer.
May 2026 in “Iconic Research and Engineering Journals” This review concluded that polyherbal hair oils, using key medicinal plants, may offer a validated and sustainable alternative to synthetic cosmetics for hair and scalp health, with potential for industrial standardization and clinical use.
In this study, researchers describe a technique for preparing mesenchymal stem cells to optimize hair transplantation for androgenetic alopecia, highlighting future plans to assess stem cell characteristics and hair density improvements through flow cytometry and trichoscopy.
August 2017 in “Journal of evolution of medical and dental sciences” In this study, researchers evaluated trichoscopy in diagnosing non-scarring alopecia and found diagnostic value in observing diverse hair diameters in androgenetic alopecia, black dots and broken hairs in alopecia areata, and empty follicles in telogen effluvium, supporting trichoscopy's utility in differentiating alopecia types.
April 2017 in “Journal of Investigative Dermatology” This study suggests that PKCß plays a critical role in modulating the dermal inflammatory microenvironment in response to dietary lipids in mice.
100 citations
,
September 1999 in “British Journal of Dermatology” This study suggests that finasteride's effect on promoting hair growth in men with androgenetic alopecia may be due to its inhibition of 5aR2 localized in hair follicles.