20 citations,
January 2017 in “Epilepsia” Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
Levetiracetam and valproate sodium both reduce seizures when added to lamotrigine, but levetiracetam has fewer side effects.
January 2008 in “Elsevier eBooks” The young woman with epilepsy became seizure-free after finding the right combination of medications.
35 citations,
August 2004 in “Epilepsy & behavior” Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
3 citations,
June 2015 in “Serbian Journal of Dermatology and Venereology” The conclusion is that cerebrovascular diseases can cause seizure-like activity in stroke patients, which can be improved with antiepileptic drugs.
October 2018 in “Emergency medicine news” A 65-year-old man with sudden abdominal pain and seizures was diagnosed with a rare, non-traumatic splenic rupture and treated without surgery.
January 2017 in “Elsevier eBooks” Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
2 citations,
October 2018 in “The journal of pediatrics/The Journal of pediatrics” The document concludes that specific hair and blood vessel abnormalities in infants with seizures and developmental issues may indicate Menkes disease, which lacks a cure and is often fatal by age 3.
48 citations,
February 1999 in “PubMed” Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
4 citations,
August 2001 in “Epilepsia” Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.
20 citations,
June 2022 in “Molecules” Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
3 citations,
August 2017 in “Synlett” Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
184 citations,
August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
137 citations,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
3 citations,
September 2016 in “Pediatric Dermatology” Hypertrichosis (excessive hair growth) can help diagnose superficial epidermolytic ichthyosis.
1 citations,
February 2021 in “Animal feed science and technology” Organic selenium may offer better retention and less waste in puppies.
January 2022 in “Indian Journal of Dermatology/Indian journal of dermatology” Valproic acid can cause dark lines on nails.
13 citations,
November 2017 in “Neurotoxicity research/Neurotoxicity resarch” Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.
2 citations,
February 2003 in “Annals of Neurology” Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
73 citations,
October 2001 in “Epilepsia” Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.
2 citations,
April 2017 in “Asian Journal of Psychiatry” Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.
August 2024 in “Intisari Sains Medis” A 17-year-old girl with lupus had vocal cord paralysis but improved with treatment.
Psychosis can be an early sign of neuropsychiatric lupus, treatable with tailored medication.
21 citations,
June 2005 in “Alcoholism: Clinical and Experimental Research” Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
13 citations,
September 2011 in “Archives of dermatology” A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.
2 citations,
April 2023 in “Curēus” Valproic acid can cause muscle damage and liver issues, which improve after stopping the drug.
1 citations,
October 2019 in “Epileptic disorders” A girl with Pitt-Hopkins syndrome developed curly hair as a rare side effect from the epilepsy drug perampanel.
March 2023 in “Scientific Reports” Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
166 citations,
November 2008 in “Expert Review of Endocrinology & Metabolism” Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
65 citations,
January 2011 in “Frontiers in Endocrinology” Neurosteroids show promise for treating epilepsy and more research is needed.