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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Microneedling alone is as effective as microneedling with platelet-rich plasma for male pattern baldness.

New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.

Managing diabetes can lead to eating disorders, and eating disorders can make diabetes harder to control.

Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.

Personalized diets, like the Mediterranean Diet and low carb diets, can help manage PCOS symptoms in obese women, and probiotics may enhance weight loss and improve metabolic health. More research is needed to find the best diet strategies.

ALRV5XR effectively increases hair density in men with androgenetic alopecia without adverse effects.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.

High-dose vitamin D3 does not improve symptoms or quality of life in COVID-19 patients after one year.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.

A child's chronic use of Senna caused liver damage and a severe decrease in blood cells, but improved after stopping Senna and getting treatment.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.

Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.

The new microwell device helps grow more hair stem cells that can regenerate hair.

Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).

New and existing treatments for hair loss show promise, with some being more effective for men and others for women.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.