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This review examines patents and publications on steroid sulfatase inhibitors since 1999 and reports no new clinical results, highlighting their potential for treating estrogen- and androgen-driven conditions.

This paper suggests intralesional cidofovir as a potentially effective treatment for SCC with no systemic toxicity observed, but surgical excision remains the standard for its curative outcomes and thorough evaluation.

This study found that super-enhancers in squamous cell carcinoma stem cells are distinctly different from those in normal skin stem cells, with ETS2 playing a crucial role in promoting tumor growth.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This overview details the Dermatologic Surgery journal's extensive coverage of dermatologic surgery topics, including cosmetic and reconstructive procedures, but it reports no new research findings.

This article reports that while surgical excision is often the best treatment for SCC, intralesional cidofovir also showed success without systemic toxicity in the case discussed.

In this study, 3D planned resection and reconstruction for skull defects after resection of cSCC with bony invasion led to accurate procedures, though patient-specific factors should guide treatment decisions.

Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.

This article discusses the potential of intralesional cidofovir as a treatment for SCC and reports no systemic toxicity, but highlights surgical excision as the most reliable curative option.

This study reported that trichoscopy can identify specific hair shaft abnormalities linked to increased serological activity, highlighting its use as a valuable non-invasive diagnostic tool in pediatric dermatology for neonates with ECS.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

This article discusses topical and intralesional cidofovir use for SCC and suggests a successful outcome in one case, with no systemic toxicity observed so far.

This case study reports that intralesional cidofovir was successfully used for treatment without systemic toxicity, suggesting it might be an option worth considering for SCC.

This review highlights the promising clinical outcomes of sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate for breast cancer that targets TROP2, demonstrating improved response rates and progression-free survival, with manageable safety concerns including primarily mild-to-moderate nausea and alopecia.

This study observed that repeated perm treatments decrease disulfide bonds in hair due to their conversion largely into cysteic acid, affecting the waving efficiency depending on the reduction agent used.

This study found that patients with central centrifugal cicatricial alopecia preferred shared decision-making with their doctors regarding treatment management.

This review discusses the role of steroid sulfatase in steroid hormone metabolism and highlights the need for more research on its expression and regulation, especially regarding hormone-dependent tumors.

This article discusses the various uses of the cotton-tipped applicator in dermatologic surgery, highlighting its innovative role as a suture scissors stabilizer, but reports no clinical results.

This article discusses the potential of intralesional cidofovir for treating SCC without systemic toxicity, noting that surgical excision remains the best treatment option; it reports no new clinical results.

Scalp cooling therapy is costly and often not covered by insurance, limiting access for low-income patients.

In this study, the researchers found that a 28-day topical treatment with a postbiotic ferment complex notably altered the scalp microbiome in women with sensitive scalps, increasing certain bacterial species and decreasing others, while also reportedly alleviating symptoms of sensitive skin syndrome in all participants.

This study concluded that the new subfractionation culturing method generates highly homogeneous adipose-derived stem cells with enhanced mitogenic, paracrine, and hair growth-promoting effects compared to traditional isolation methods.

The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.

In this case study, the use of somatostatin analogues was effective in localizing and confirming a neuroendocrine lung tumor as the source of ectopic ACTH syndrome, leading to marked clinical improvement in a patient unable to undergo surgery.

In this review, the authors found that cannabinoids and steroid-related drugs show potential for treating Tourette syndrome, but existing evidence is limited and further research is needed to confirm their efficacy and safety.

This case report details two siblings with trichothiodystrophy, identifying reduced hair sulfur content as essential for diagnosis despite varied symptoms complicating recognition.

This study suggests that intralesional cidofovir might be a treatment option for SCC, as it showed a successful outcome without systemic toxicity in the reported case.

This article proposes two new categories of cicatricial alopecia—“unstable” and “stable”—and suggests surgical excision as preferred over hair transplantation, especially for unstable cases.

This study introduced the C-CAT, a new assessment tool for central centrifugal cicatricial alopecia, and found that established treatments improved symptoms in most patients over six months.

In this study, L-cysteine treated with the Trivedi Effect® showed significantly increased isotopic abundance ratios, which may enhance its stability and shelf-life.