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Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Targeted cancer therapies often cause serious skin problems that need careful management.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Zinc is effective for treating various skin conditions, including warts and acne.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Treatments for melanin disorders exist, but more effective options needed.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Minoxidil foam enters hair follicles and skin for hair growth.