research Effect of Allopregnanolone and Allotetrahydrodeoxycorticosterone on Spike-Wave Discharges in the EEG of Absence Epilepsy Rat Models
The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
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research Phloroglucinol Enhances Anagen Signaling and Alleviates H2O2-Induced Oxidative Stress in Human Dermal Papilla Cells
Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.
research Ethosome as a Potential Transdermal Drug Delivery System
Ethosomes are a promising way to deliver drugs through the skin.
research Forensics in Dermatology: Part II
Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Status of Serum Vitamin D Level Among Patients With Alopecia Areata in a Tertiary Care Hospital, Bangladesh
People with alopecia areata have much lower Vitamin-D levels than healthy individuals.
research Teriflunomide Efficacy, Safety, and Tolerability in Patients with Relapsing Forms of Multiple Sclerosis
Teriflunomide is effective and generally safe for treating relapsing multiple sclerosis, reducing relapse rates and disability progression.
research Human Basal Cell Carcinoma: The Induction of Anagen Hair Follicle Differentiation
Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.
research Finasteride in Androgenic Alopecia
Finasteride treats hair loss but may cause side effects like low libido and dizziness.
research Beyond Testosterone Cypionate: Evidence Behind the Use of Nandrolone in Male Health and Wellness
Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
research 5-Alpha Reductase Inhibitors in Androgenetic Alopecia: Shifting Paradigms, Current Concepts, Comparative Efficacy, and Safety
Dutasteride works better than finasteride for hair loss, with both being safe to use.
research Fluridil, A Rationally Designed Topical Agent For Androgenetic Alopecia: First Clinical Experience
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research Cutaneous Manifestations in Biologically Treated Inflammatory Bowel Disease Patients: A Narrative Review
Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.
research Guidelines for Perioperative Antithrombotic Therapy in Hair Restoration Surgery: Management of Patients with Coronary Heart Disease, Mechanical Heart Valve, and Atrial Fibrillation
Hair restoration surgery can be safely done without major bleeding in patients on antithrombotic therapy, and these drugs shouldn't be stopped before surgery.
research Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome
Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.
research Microbial Biosurfactant as an Alternative to Chemical Surfactants for Application in Cosmetic Industries in Personal and Skin Care Products: A Critical Review
Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Recent Progress in Understanding the Effect of Sympathetic Nerves on Hair Follicle Growth
Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.
research Short Scar Rhytidectomy Techniques
New facelift techniques lead to less scarring and faster recovery, with high patient satisfaction after 4 years.
research Acute Selenium Poisoning by Paradise Nuts (Lecythis Ollaria)
Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.
research Baricitinib: From Rheumatoid Arthritis to COVID-19
Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
research Insulin Resistance and Skin Diseases
Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Does Estradiol Level in Platelet-Rich Plasma Improve Efficacy of Androgenic Alopecia Treatment?
Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.