39 citations,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
30 citations,
May 2010 in “British Journal of Dermatology” Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.
19 citations,
October 2017 in “The FASEB Journal” Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
13 citations,
July 2004 in “Skinmed” Common types of non-scarring hair loss have various causes and treatments, but more effective solutions are needed.
55 citations,
April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
24 citations,
January 2006 in “Skin Pharmacology and Physiology” Finasteride reverses early hair loss and promotes growth.
24 citations,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
24 citations,
March 1995 in “British Journal of Dermatology” Etretinate therapy can cause hair loss by disrupting the hair growth cycle.
45 citations,
December 1991 in “Annals of the New York Academy of Sciences” ECM molecules are crucial for hair growth and development.
100 citations,
September 2017 in “Molecular and Cellular Endocrinology” Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
17 citations,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
34 citations,
December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
July 2023 in “Journal of Drug Delivery Science and Technology” Finasteride niosomes were developed and found to be effective in treating hair loss, with better results than commercial minoxidil, and could be a promising topical treatment for hair loss.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
4 citations,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
1 citations,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
December 2007 in “CRC Press eBooks” Alopecia areata incognita causes widespread hair loss without patches and needs a scalp biopsy for diagnosis.
51 citations,
October 2002 in “Archives of dermatology” The document does not conclude the effectiveness of the 800-nm pulsed-diode laser for treating scalp cellulitis.
August 2022 in “Nutrients” Nutritional supplements may help improve hair growth in female pattern hair loss.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
January 2015 in “American journal of medical and biological research” 159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
11 citations,
January 2001 in “Cambridge University Press eBooks” Androgens can cause hair growth in some areas but hair loss on the scalp.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
6 citations,
August 2006 in “Journal of Cutaneous Pathology” Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
32 citations,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
139 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Androgenetic alopecia in women needs more research and better management strategies.