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Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Manatee whiskers are specially adapted for touch in water.

5-Alpha-Reductase Inhibitors can cause negative side effects.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

A male with aromatase deficiency improved bone health with estradiol treatment.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.

Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.

Pro-IGF-II improves muscle repair in old mice.

Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Darkened knuckles can be an early sign of insulin resistance.

The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.

Recreational drug use can cause misdiagnosed conditions and drug interactions in HIV patients.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.