22 citations
,
November 2018 in “Breast Cancer Research and Treatment” In this review, researchers found no evidence of interactions between 5α-reductase inhibitors or spironolactone and endocrine therapies for breast cancer, with no consistent changes in estrogen levels or increased breast cancer risk associated with spironolactone usage.
21 citations
,
October 2023 in “Journal of Dermatological Treatment” The abstract provides a brief mention of alopecia areata (AA) being a chronic immune-mediated disorder causing non-scarring hair loss, but specific study results or findings relating to this are not reported.
21 citations
,
December 2022 in “Pharmaceutics” This review found that laser-assisted drug delivery in humans was associated with several adverse effects, but no life-threatening events were reported in the studies examined.
21 citations
,
January 2021 in “Journal of infection and chemotherapy” This study observed that male sex, diabetes mellitus, and high maximum C-reactive protein levels during the acute phase of COVID-19 were linked to elevated anti-SARS-CoV-2 antibody levels.
20 citations
,
December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This article presents a computer imaging algorithm that may automate and enhance the Severity of Alopecia Tool scoring for alopecia areata through texture analysis of pediatric images.
20 citations
,
February 2023 in “American Journal of Clinical Dermatology” In this study, 40.9% of patients taking 4 mg baricitinib and 21.2% taking 2 mg achieved significant hair regrowth over 52 weeks, indicating potential long-term benefits for adults with severe alopecia areata without introducing new safety concerns.
20 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified six approved drugs that inhibited spike-mediated cell entry, potentially offering effective treatments against the initial stage of SARS-CoV-2 infection.
20 citations
,
June 2019 in “Archives of dermatological research” In this study, combination therapy with DPCP and anthralin promoted hair regrowth in 40.62% of alopecia areata patients who were unresponsive to DPCP alone, with response improving over longer treatment durations.
20 citations
,
June 2003 in “Neurology” This case report describes improvement in amenorrhea, alopecia, and muscle spasms in a 13-year-old girl with Satoyoshi syndrome following treatment with daily tacrolimus and alternate-day oral prednisolone.
19 citations
,
July 2019 in “Journal of Endocrinology” This study found that GTx-024 and Danazol had similar effects to dihydrotestosterone on uterine tissue in mice, while GTx-007 showed minimal impact on the parameters tested.
19 citations
,
December 2018 in “Experimental and Molecular Medicine” This study reports that the novel small molecule IM176OUT05, by modifying stem cell metabolism, promoted hair regrowth and increased hair follicle numbers in mice.
19 citations
,
March 2018 in “Expert Opinion on Drug Safety” In this narrative review, the researchers reported that the overall safety profile of drugs used for treating spondyloarthritis is generally good, with serious adverse events being rare, but emphasized the need for rheumatologists to tailor treatments and closely monitor patients for potential adverse events.
19 citations
,
January 2016 in “Annals of Dermatology” This study found that dutasteride 0.5 mg was generally well-tolerated and led to overall improvement in male patients aged 18 to 41 with androgenic alopecia in a Korean clinical practice setting.
19 citations
,
June 2007 in “Veterinary Dermatology” In this study, amitraz was found to be an effective and well-tolerated treatment for resolving sarcoptic mange in alpacas, demonstrating no relapse over a 10-month follow-up.
18 citations
,
May 2017 in “Head & Neck” This study reported that free tissue transfer for postcranioplasty implant exposure led to a 100% free flap survival rate and salvaged 91% of the implants without removal, suggesting it is a highly effective reconstructive option even for chronic cases.
18 citations
,
April 2014 in “Stem cells” The researchers reported that minor salivary gland stem cells exhibit stem cell characteristics and respond to tobacco-derived carcinogens, implicating the transforming growth factor beta pathway in their maintenance.
18 citations
,
February 2023 in “Plants” This study found that PES1CMU-defatted rice bran (DFRB) showed effective skin whitening and anti-aging properties comparable to standard treatments in cell models, suggesting its potential use in dermatocosmetics.
18 citations
,
July 2020 in “Basic and Clinical Andrology” This article discusses concerns and recommendations from a French-speaking andrology society regarding COVID-19's potential impact on men's reproductive health and calls for further research in this area.
18 citations
,
November 2017 in “International Journal of Cosmetic Science” This study found that Bio Skin Oil® reduced the appearance of non-keloid scars and striae, with significant improvements observed by both investigators and participants.
18 citations
,
January 2016 in “Elsevier eBooks” This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.
18 citations
,
August 2012 in “Clinical and Experimental Dermatology” This study concluded that a 3% IGF-1 liposomal gel improved hair thickness and growth in hamsters without inducing significant hepatotoxicity or myelotoxicity, suggesting its potential as a safe hair-loss treatment.
18 citations
,
February 2006 in “Brain & development” This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.
18 citations
,
January 2001 in “Annual Reports in Medicinal Chemistry” This chapter reviews selective androgen receptor modulators, discussing their therapeutic potential beyond current androgen applications, and reports no new clinical findings.
17 citations
,
November 2002 in “Australasian Journal of Dermatology” This case report describes a 24-year-old woman with androgenetic alopecia who developed sensitivity to topical minoxidil and later to saw palmetto after using a minoxidil and retinoic acid preparation.
17 citations
,
August 2021 in “Dermatologic surgery” This review found that microneedling is generally safe, with most adverse effects being minor and resolving quickly, though there is increased risk in patients with active infections, darker skin, or metal allergies.
17 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” In this study, once-daily treatment with bimatoprost 0.03% solution significantly increased eyelash growth, thickness, and darkness in patients with chemotherapy-induced eyelash loss compared to placebo, and was well tolerated over one year.
16 citations
,
July 2022 in “The Laryngoscope” This study found that platelet-rich plasma injections for vocal fold scarring and atrophy showed a favorable safety profile and subjective improvements in vocal quality and fatigue over a three-month follow-up.
16 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This abstract discusses the efficacy of spironolactone, cyproterone acetate, and flutamide in treating female pattern hair loss, noting that flutamide use requires caution due to potential liver toxicity, especially at high doses.
16 citations
,
June 2019 in “Journal of Investigative Dermatology” The researchers reported that miR-21 expression increases with age in both human and mouse skin and may contribute to skin aging by targeting the chromatin remodeler SATB1 in keratinocytes.
16 citations
,
January 2010 in “Drug Metabolism and Pharmacokinetics” This study developed a pharmacokinetic/pharmacodynamic model for finasteride, concluding that finasteride's nonlinear pharmacokinetics are likely due to its saturable binding to 5alphaR2.