August 2026 in “Dermatology and Therapy” This study conducted in the Kingdom of Saudi Arabia reported that severe alopecia areata presents significant treatment challenges due to limited therapies, leading to substantial impacts on patients' quality of life, mental health, and economic burdens.
2 citations
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April 2021 in “Cureus” This study developed two highly reliable Arabic HRQoL questionnaires for evaluating quality of life in married and unmarried women with polycystic ovary syndrome.
196 citations
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May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that SZ95 sebocytes and HaCaT keratinocytes exhibit distinct enzyme expressions and activities, implicating their different roles in androgen metabolism and homeostasis in vitro.
This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
1 citations
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January 1999 in “Dermatology” 1 citations
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May 2024 in “Communications Biology” This study found that Dab2 conditional knockout mice experienced delayed hair follicle cycles and reduced hair follicle stem cell activity, suggesting Dab2's crucial role in regulating stem cell activation and anti-aging process in hair follicles.
76 citations
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September 1992 in “Endocrinology” This study details the isolation and characterization of the human type II 5 alpha-reductase gene, which may play a role in male pseudohermaphroditism, prostate cancer, and benign prostatic hyperplasia.
20 citations
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October 2005 in “Archives of Dermatological Research”
15 citations
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April 2003 in “Journal of Dermatological Science” This study found no significant associations between the polymorphisms of SRD5A1 and SRD5A2 genes and androgenetic alopecia, clinical types of baldness, or response to finasteride in Koreans.
April 2026 in “Communications Biology” In this study of Danioninae species, researchers reported that the presence of breeding tubercles on the pectoral fins is conserved in certain species and linked to local androgen conversion, with steroid 5-α-reductase playing a crucial role in their development.
May 2003 in “Hair transplant forum international” This abstract discusses an ISHRS event on hair transplantation but presents no new research findings.
1 citations
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January 2014 This review discusses SAHA syndrome in women, characterized by seborrhea, acne, hirsutism, and/or androgenetic alopecia, and notes its similarity to polycystic ovary syndrome without reporting new clinical results.
56 citations
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November 2007 in “Molecular and cellular endocrinology” This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.
August 2024 in “American Journal of Medical Genetics Part A” In this case study, researchers detailed two Saudi cases of the ultra-rare Trichohepatoneurodevelopmental syndrome, identifying pathogenic variants in the CCDC47 gene and reinforcing a strong gene-disease association, which helps clarify the disorder's clinical features and genetic mutations.
64 citations
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March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes GPRC5D's unique expression pattern in tissues that produce hard keratin, with retinoic acid inducing its expression in hair bulb cells and affecting keratin gene regulation.
44 citations
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August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
July 2017 in “Hair transplant forum international” This article reports on the 5th meeting of the AAHRS and Live Surgery Workshop, held in a scenic location but does not provide new research findings.
July 2018 in “Hair transplant forum international” This abstract contains only author affiliations and mentions the Asian Association of Hair Restoration Surgeons, without presenting any new research findings.
April 2025 in “The Egyptian Journal of Surgery” This study found that the SASJ procedure is a safe and effective bariatric approach, resulting in significant weight loss, improvement in obesity-related comorbidities, and a low risk of postsurgical complications over one year.
6 citations
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July 2024 in “Heliyon” This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.
21 citations
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July 2011 in “Journal of the American Academy of Dermatology” This study reported a drug-induced pityriasis rubra pilaris-like eruption in a patient treated with sorafenib, suggesting a possible effect of sorafenib on keratinocyte biology.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that engineered high-affinity soluble CD200R agonists, including ARQ-234, showed superior efficacy in reducing immune responses in various preclinical models of inflammatory conditions, suggesting potential as a therapeutic for atopic dermatitis and other related diseases.
10 citations
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December 2011 in “PubMed” In this reported case of SAPHO syndrome, methotrexate treatment led to significant clinical improvement after other treatments for skin lesions and arthritis proved less effective.
December 2025 in “Biomolecules” This study reviews the emerging role of protein S-palmitoylation in dermatology, highlighting its impact on skin functions like inflammation and barrier maintenance, and evaluating its potential as a therapeutic target for skin disorders such as alopecia and psoriasis.
19 citations
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September 2011 in “Journal of Dermatological Science” TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.
13 citations
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November 2009 in “Journal of Dermatological Science” This article discusses various dermatological studies cited by previous authors and reports no new clinical results.
January 2025 in “International Journal of Veterinary Sciences and Animal Husbandry” In this case study, researchers found that treatment with sarolaner led to complete recovery from generalized demodicosis in six dogs within four weeks, resolving clinical signs without adverse reactions.
44 citations
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October 2009 in “Journal of the American Academy of Dermatology” This study reported that 1% bexarotene gel was well tolerated and possibly effective for inducing partial hair regrowth in alopecia areata, but more rigorous trials are needed to confirm its efficacy.
This study identified several compounds, including Pictilisib and Nimorazole, that may have higher binding affinity for SARS-CoV-2 main protease than existing inhibitors, potentially offering new treatment alternatives for Covid-19.
July 2023 in “Jurnal Ilmu Kesehatan Hewan” In this case report, a 2-month-old dog with scabies showed improvement in skin condition and reduced mite presence 24 days after treatment with simparica, sulfur-based soap, and various topical and oral therapies.