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This review discusses the therapeutic potential of MSC-derived secretomes for treating degenerative and inflammatory diseases, reporting no new clinical results but highlighting their proposed mechanisms and advantages over direct MSC transplantation.

In this study, the prevalence of polycystic ovary syndrome among Han Chinese women aged 19-45 was found to be 5.6%, and PCOS was associated with increased metabolic risks, particularly in obese individuals.

This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.

This study reveals that overexpression of Wnt3 in transgenic mouse skin leads to a short-hair phenotype and cyclical balding due to structural defects in hair shafts, highlighting a role for WNT signaling in hair growth regulation.

This study found that PCOS patients had higher amounts of central abdominal fat compared to weight-matched controls, which was associated with increased insulin resistance.

This review discusses the cosmetic and nutricosmetic efficacy of hyaluronic acid for skin rejuvenation and reports that HA formulations show remarkable anti-aging properties.

This review examines the challenges of cell engraftment in regenerative medicine and discusses potential strategies to improve the efficacy of cell-based therapies, including cell-free regenerative approaches.

This study observed that acute stress in rats increased neurosteroid levels linked to enhanced GABA(A) receptor function, raising seizure thresholds, while similar effects were seen in mice with deoxycorticosterone administration.

In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.

In this study, researchers found that YAP and TAZ, when localized in the nucleus of basal layer cells, are crucial for skin regeneration and hair growth, with their loss leading to slower cell proliferation, hair loss, and impaired wound healing in mice.

This article outlines the rationale and design of the Rotterdam Study, summarizes its major findings, and updates its objectives and methods; it reports no new research results.

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

This study found that ZnO nanoparticles in topical skin products do not penetrate beyond the outer skin layers in humans, suggesting minimal safety concerns for subdermal absorption.

This paper discusses the potential roles of adipose tissue derived stem cells in skin regeneration and wound healing but emphasizes the need for further research on their effectiveness in clinical settings.

This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.

This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.

Stress can cause hair to turn gray by depleting stem cells.

This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.

This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.

This study identifies mutations in the SRD5A3 gene as a cause of a new type of congenital disorder of glycosylation, impacting mental, ophthalmologic, and cerebellar functions.

This review provides graded evidence and a therapeutic algorithm for managing hidradenitis suppurativa, but does not present new clinical results.

This article reviews recent insights into the regulatory role of reactive oxygen species in plant development, highlighting that their mechanisms and signaling pathways remain partially understood.

This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.

This study found that Notch signalling promotes differentiation of epidermal cells and acts as a tumour suppressor in the skin by interacting with various pathways and mechanisms.

This study suggests that programmed cell death plays a crucial role in shaping the structure of the human epidermis and its appendages during development.

This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.

This study suggests that fibroblast growth factors FGF-4, FGF-8, and FGF-9 may play redundant roles as signals in epithelial-mesenchymal interactions during multiple stages of tooth development in mice.

Blocking EGFR in mice causes hair loss and skin changes.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.