research Effect of Site of Defect on Completeness of Regeneration of the Rat's Skin
The location of a skin injury affects how well a rat's skin can heal.
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540-570 / 1000+ results research Is Finasteride Intake Associated with Penile Curvature/Peyronie’s Disease? Assessment of Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases
research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche
The study investigated the pathogenesis of lichen planopilaris (LPP), a chronic inflammatory disease causing permanent hair loss, by analyzing scalp biopsies from 42 adult patients. It found that LPP is characterized by the collapse of immune privilege in the hair follicle's epithelial stem cell niche, known as the bulge. This collapse was evidenced by increased expression of MHC class I and II and a Th1-biased cytotoxic T cell response, alongside increased proliferation and apoptosis of epithelial hair follicle stem cells (eHFSCs). The findings suggested that interferon-γ (IFNγ) plays a significant role in this process, indicating that LPP may be an autoimmune disease. The study proposed that protecting or restoring immune privilege in the bulge could be a therapeutic strategy for managing this treatment-resistant form of cicatricial alopecia.
research Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study
Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
research Comparison of Clinical and Laboratory Characteristics of Cases with Polycystic Ovarian Syndrome Based on Rotterdam’s Criteria and Women with Only Oligo/Anovulation or Hirsutism
Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
research Case Series of Oral Minoxidil for Androgenetic and Traction Alopecia: Tolerability and the Five C’s of Oral Therapy
Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.
research ‘You Lose Your Hair, What’s the Big Deal?’ I Was So Embarrassed, I Was So Self-Conscious, I Was So Depressed: A Qualitative Interview Study to Understand the Psychosocial Burden of Alopecia Areata
Alopecia Areata (AA) causes significant emotional distress, including feelings of embarrassment, depression, and anxiety, and impacts social interactions and daily activities.
research The Challenges with Managing Polycystic Ovary Syndrome: A Qualitative Study of Women’s and Clinicians’ Experiences
Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.
research The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men's Health
Hair loss drugs may cause sexual issues and infertility in men.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?
Topical minoxidil improves hair loss in 80% of women with breast cancer undergoing endocrine therapy.
research A Novel Mutation in the FERMT1 Gene in a Spanish Family with Kindler’s Syndrome
Researchers found a new mutation in the FERMT1 gene in a Spanish family with Kindler syndrome.
research Ability to Cycle Despite Severe Freezing of Gait in Atypical Parkinsonism in Fahr's Syndrome
Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
research End of Life Care in Inpatient Psychiatry: A Case Study on End-Stage Alzheimer's Disease
The case shows the need for psychiatrists to manage end-of-life care for dementia patients, including respecting patients' wishes and using hospice services.
research Safety and Tolerability of Antiepileptic Drugs in Women with Epilepsy
Antiepileptic drugs can cause side effects like menstrual problems and infertility in women with epilepsy, but most pregnancies result in healthy babies, with newer drugs being safer.
research The Utility of the Classification Tools in National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries for Primary Care
Nearly half of the classification tools in the National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries might not effectively guide management for general practitioners.
research Treatment Patterns and Unmet Needs in the Management of Alopecia Areata: Results of a Physician’s Survey in the Middle East
Doctors in the Middle East need better treatments and more knowledge about new therapies for hair loss condition Alopecia Areata.
research Impact of the SARS-CoV-2 Pandemic on Climacteric Women's Health: Websurvey
The pandemic worsened mental health and healthcare access for middle-aged women, leading to negative changes in their lifestyle.
research Methodology for Assessing the Impact of Innovations on the Production of the Region's Final Products
The document provides a way to measure how new ideas affect the making of goods in a region.
research Recovery of Resistant Alopecia Areata Treated with Tofacitinib: An 8-Year-Old Child's Case Report
Tofacitinib helped an 8-year-old child recover from a type of hair loss that is hard to treat.
research Activity Test of Aloe Vera Peel Extract Gel on Rabbit's Minor Burns
Aloe vera peel extract gel helps speed up the healing of minor burns in rabbits.
research Use and Misuse of PRP: Clinical Trial Proposal to Determine PRP’s True Efficacy
The document suggests a clinical trial to accurately determine if PRP is an effective treatment for a common type of hair loss in men.
research Advances in Cosmetic Dermatology
The book provides an overview of new trends and techniques in cosmetic dermatology.
research Childhood Trichotillomania: Diagnostic Algorithm and Systematic Problem-Solving Management Using the 5W1H (Kipling’s Principle)
The conclusion is that using the 5W1H method can improve diagnosis and management of childhood hair-pulling disorder.
research Letters to the Editors: Re: Dr. Jerry Cooley’s, 'Bio-Enhanced Hair Restoration'
Unable to summarize as the document content is not provided.
research Effects of Lipid and Acne Inhibitive Cream on Acne Model of Rabbit's Ears
LAIC cream can improve acne by making skin thinner and softer.
research Effect of Compound Diandao Pulvis Drug Facial Mask on Acne Model of Rabbit's Ears
CDPDFM can improve acne symptoms in rabbit ears.
research Differentiated Application of Oral Contraceptives Based on the Different Side Effects of Synthetic Progestins
Choose oral contraceptives with specific side effects to manage issues like acne and avoid unwanted effects.
research Community Pharmacy and Hospital Pharmacy Internship Reports and Monograph: Counseling for Androgenetic Alopecia – The Pharmacist’s Role
research Quality of Life Assessment in Patients with Alopecia Areata and Androgenetic Alopecia in the People's Republic of China
Hair loss from alopecia areata and androgenetic alopecia moderately affects the quality of life, especially in younger patients and those with long-term hair loss, impacting both their physical and emotional well-being.