Use and Misuse of PRP: Clinical Trial Proposal to Determine PRP’s True Efficacy

The document from 5 years ago proposed a clinical trial to determine the true efficacy of Platelet-rich plasma (PRP) as a treatment for androgenetic alopecia (AGA), a common type of hair loss in men. PRP, known for its regenerative properties, has been used in various fields since the 1970s and in dermatology, it's been applied to different hair diseases. However, the document noted that the protocol for producing PRP varied greatly among researchers and its effectiveness was not clearly demonstrated, especially in AGA treatment. The authors conducted a retrospective systematic review of the literature and proposed a randomized placebo-controlled, double-blind, half-head study clinical trial with a uniform PRP obtaining methodology to properly assess its efficacy as a future AGA treatment.