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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Latanoprost can make eyelashes longer, thicker, and darker.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

New treatments targeting specific genes show promise for treating keratin disorders.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Mutant mice help researchers understand hair growth and related genetic factors.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Hair follicle regeneration needs special conditions and young cells.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Certain genes control the color of human hair by affecting pigment production.

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.