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This review highlights recent progress in developing androgen receptor degraders, such as PROTACs, for treating castration-resistant prostate cancer, and notes that several have entered phase I or II clinical trials, showcasing potential to address drug resistance challenges.

This study observed that root hair growth in Arabidopsis occurs episodically, with each growth period associated with external alkalization and internal acidification, suggesting a role for proton influx in facilitating polar growth.

This study found that KROX20 is crucial for hair follicle development and epidermal homeostasis, as its deletion in skin epithelial cells led to hair loss and increased epidermal thickness.

In this study, topical 5% roxithromycin was effective in restoring hair growth in about half of individuals with androgenetic alopecia without causing adverse effects.

In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.

This study found that a newly developed biocompatible hydrogel, responsive to reactive oxygen species, enabled targeted delivery of miR-665, significantly promoting hair regeneration and reducing T-cell infiltration in a mouse model of alopecia areata, suggesting a promising strategy for treating this condition.

This study reported that mannan oligosaccharides improved the fur quality, immune response, antioxidant status, and gut microbiota of fur-growing raccoon dogs, suggesting they could potentially replace antibiotics in their diet.

In this study, the researchers reported that Krox20 plays a crucial role in epidermal homeostasis and hair development, influencing stem cell maintenance and cell survival through the modulation of cellular pathways.

This article reviews two cases of monilethrix in siblings, detailing their clinical and dermatoscopic characteristics, but reports no new findings.

This study found that RSL4 in Arabidopsis thaliana regulates genes necessary for root hair elongation by controlling proteins involved in cell signaling, cell wall modification, and secretion.

Developing microRNA-based treatments is hard but has potential.

This study found that ocu-miR-205 influences hair follicle density in Rex rabbits by promoting dermal papilla cell apoptosis and transforming hair follicles from growth to resting phases through signaling pathway modulation.

This study describes a new mite species from marmots in a city park in Washington, noting that infested marmots displayed significant hair loss and tissue abnormalities.

This study identified multiple mutations in the 5 alpha-reductase-2 gene among male pseudohermaphrodites in the Dominican Republic, suggesting they do not share a common ancestry.

In this review, the authors highlight the involvement of the 5α-reductase enzyme family in androgen-dependent disorders, noting the discovery of a novel isoform, SRD5A3, which is overexpressed in cancers with poor prognosis.

This study reports that localized Rho GTPase activity and ROS production play a critical role in polarized growth and movement in both migrating endothelial cells and developing plant root hairs.

This study found that unripe Rubus occidentalis extracts may inhibit benign prostatic hyperplasia development in a rat model by reducing prostate weight and androgen-related gene expression.

This study suggests that subtle modifications in ribosomal RNA methylation may influence cellular physiology and contribute to ribosome specialization in senescent human dermal fibroblasts.

This study identified various therapeutic applications of rosemary in humans, including cellular, dental, dermatological, metabolic, respiratory, and nervous system conditions, supporting its potential in evidence-based medicine.

This study identified Azithromycin and Roxithromycin as novel senolytic antibiotics that effectively target and reduce senescent human fibroblast cells.

In this study, trichoscopy highlights that hair diameter variability, vellus hairs, and the peripilar sign are key indicators for diagnosing androgenetic alopecia.

This historical review traces the discovery of 5-alpha reductase inhibitors, widely used in urology, from the study of guevedoces, Dominican children with a rare disorder leading to significant androgenization at puberty.

This case report documents a dog with dermatophytosis, caused by the fungus Microsporum canis, presenting symptoms like alopecia in the neck and ear, highlighting the condition's prevalence in tropical and temperate climates and its zoonotic nature.

In this study, researchers investigated changes in ribosomal RNA modifications associated with stress-induced cellular senescence in human skin cells, identifying potential biomarkers and targets for interventions to mitigate skin aging.