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Breathing in high levels of certain air pollutants significantly increases women's risk of developing Polycystic Ovary Syndrome.

Some birth control pills increase young women's risk of blood clots more than others.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Women with hair loss have higher heart disease risk and unhealthy cholesterol levels.

Skin diseases like psoriasis, lupus, and others can increase heart disease risk due to factors like chronic inflammation and genetic susceptibility.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.

Coloring shampoos for gray hair may cause gene mutation, reproductive issues, and skin damage, needing stricter regulation and expert consultation.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride and dutasteride increase sexual dysfunction risk by 1.57 times in male hair loss treatment.

Using hair dye may slightly increase the risk of non-Hodgkin's lymphoma, especially with long-term use.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Higher levels of small, dense LDL cholesterol are linked to a greater risk of heart attack in young adults.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

A specific gene variant is linked to a higher risk of hair loss from chemotherapy in breast cancer patients.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.

Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.