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Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Advanced human skin models improve drug development and could replace animal testing.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.