April 2026 in “World Allergy Organization Journal” This study found that allergic rhinitis is linked to a higher risk of developing androgenetic alopecia, while second-generation H1-antihistamine use was associated with a reduced risk, especially in younger patients.
5 citations
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December 2020 in “Materials Research Express” This study found that silver nanoparticles biofabricated using Ostericum koreanum leaf extract inhibited inflammatory cytokine production in stimulated human mast cell lines, suggesting potential use in treating mast cell-mediated allergic diseases.
March 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case study, treatment with the selective JAK1 inhibitor upadacitinib significantly improved symptoms in a patient with refractory alopecia areata, vitiligo, ankylosing spondylitis, and allergic asthma-nasal syndrome, though a transient liver function abnormality was noted.
16 citations
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September 2004 in “Pediatric dermatology” This study found that children and adolescents with allergic diseases have significantly longer eyelashes compared to nonallergic controls.
February 2017 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study reports a case where subcutaneous aeroallergen immunotherapy led to hair regrowth in a child with seasonal alopecia areata linked to rhinitis and allergen sensitivity, maintaining results over four years with some residual symptoms.
2 citations
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July 2024 in “Indian Journal of Dermatology Venereology and Leprology” This study reported that Taiwanese pre-teens and teenagers with atopic diseases, such as food allergies and asthma, had a significantly increased risk of developing alopecia areata, with the risk being 9.66 times higher compared to their peers without atopic conditions.
27 citations
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March 2018 in “Allergy and asthma proceedings” This study found that Israeli patients with alopecia areata had a higher prevalence of comorbid conditions, including food allergies and chronic spontaneous urticaria, compared to matched controls.
35 citations
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November 2022 in “The Journal of Dermatology” This study found that the prevalence of alopecia areata in Japan increased from 2012 to 2019, with allergic diseases as common comorbidities and a need for more effective treatments, particularly for severe and pediatric cases.
8 citations
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October 1989 in “Journal of the American Academy of Dermatology” In this study, researchers observed that purpuric, telangiectatic, lichenoid balanitis was the most common histologic pattern in cases of chronic pseudoerythroplastic balanitis, suggesting a possible link to lichen aureus.
3 citations
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January 2019 in “Skin Appendage Disorders” This review of 32 articles suggests a stronger association between alopecia areata and allergic rhinitis than asthma in both adults and children, indicating a potential Th2-mediated component.
1 citations
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June 2025 in “Journal of Patient Experience” This study found that Finnish individuals with alopecia areata, especially those with significant hair loss, reported reduced well-being and significant comorbidities, highlighting unmet needs for treatment and professional support.
April 2026 in “Boletín Médico Del Hospital Infantil de México (English Edition)” This study found that 90% of pediatric patients with alopecia areata had comorbidities, including allergic rhinitis and atopic dermatitis, with localized AA being associated with better treatment outcomes and fewer relapses compared to non-localized forms.
January 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this retrospective cohort study, researchers found that Taiwanese mothers with atopic dermatitis face higher risks of various pregnancy complications, such as premature labor and preeclampsia, while their children have increased risks of conditions like asthma and ADHD compared to mothers without atopic dermatitis.
April 2024 in “Indian Journal of Paediatric Dermatology” This study in Singapore found that alopecia areata generally does not significantly impact the quality of life for pediatric patients and their families, with better outcomes observed in those with comorbidities like allergic rhinitis.
19 citations
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April 2018 in “International Journal of Dermatology” This study found that female patients with frontal fibrosing alopecia are significantly more likely to have systemic lupus erythematosus compared to controls.
4 citations
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December 2024 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this retrospective cohort study, researchers found that Taiwanese mothers with atopic dermatitis had a higher risk of various pregnancy complications and that their children were more likely to develop certain conditions like AD, asthma, and ADHD, compared to non-AD mothers and their children.
2 citations
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December 2022 in “Journal of the American Academy of Dermatology” This study reported that in Hispanic/Latinx patients with alopecia areata, rheumatoid arthritis was a common autoimmune comorbidity, and gastroesophageal reflux disease was notably more prevalent than in other populations with alopecia areata.
1 citations
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April 2024 in “Russian Journal of Clinical Dermatology and Venereology” In this study, children with alopecia areata and comorbid atopic diseases experienced an earlier onset of the condition and were more likely to develop severe forms compared to those without atopy.
1 citations
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June 2023 in “Journal of Dermatology” This study found that patients with alopecia areata had a higher prevalence of autoimmune, inflammatory, and mental health conditions compared to a matched cohort without alopecia areata.
April 2025 in “Anais Brasileiros de Dermatologia” Abrocitinib effectively treats severe alopecia areata with significant improvement and no side effects.
November 2024 in “The Journal of Dermatology” This study found that atopic diseases such as atopic dermatitis, asthma, and allergic rhinitis increase the risk of developing alopecia areata, suggesting a significant role for T cell-related inflammation in the condition's mechanism.
November 2023 in “Medical Immunology (Russia)” In this study, researchers found that children with alopecia areata exhibited immune system imbalances, including increased autoimmune and allergic markers and decreased phagocytic activity, along with a higher prevalence of autoimmune thyroiditis and allergic rhinitis compared to children without alopecia.
November 2023 in “International Journal of Dermatology” In this study, CCCA patients were found to have higher odds of metabolic, autoimmune, atopic, and psychiatric comorbidities compared to matched controls.
July 2023 in “Skin Research and Technology” This study reports that combining baricitinib with low-dose cyclosporine and steroids resulted in effective and safe treatment for a case of alopecia totalis, maintaining hair regrowth without adverse effects.
February 2023 in “Journal of vaccines and immunology” This article reviews the clinical features and potential associated conditions of alopecia areata, including its progression and histopathological characteristics, but reports no new clinical findings.
36 citations
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January 2015 in “Clinical and Translational Allergy” This review discusses allergic reactions to pollen in dogs, cats, and horses and suggests that these animals' spontaneous allergies could serve as models for translational clinical studies applicable to human allergies.
24 citations
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August 2017 in “Prostaglandins & Other Lipid Mediators” This review discusses the potential roles of prostaglandin D2 and its receptor CRTH2 in various diseases beyond allergies and asthma and reports no new clinical results.
December 2023 in “International Journal of Dermatology” This study found an increased risk of asthma and allergic rhinitis in individuals with hidradenitis suppurativa.
50 citations
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March 2021 in “Journal of investigational allergology & clinical immunology” This review examines existing research and clinical trials on the use of dupilumab for various skin, respiratory, and gastrointestinal disorders, but it reports no new clinical findings.
15 citations
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April 2020 in “Intestinal Research” This study observed that fecal microbiota transplantation for ulcerative colitis may also offer incidental benefits such as weight loss, improved hair loss, and relief from axial arthritis and allergic rhinitis.