Successful Treatment of Severe Diffuse Alopecia Areata with Abrocitinib

April 2025 in “ Anais Brasileiros de Dermatologia ”

Jinran Lin, Zheng Li, Linxia Shen, Jui‐Ming Lin, Ke Tao, Ying Miao, Chunya Ni, Youyu Sheng, Wenyu Wu

abrocitinib alopecia areata JAK1 inhibitor Severity of Alopecia Tool SALT score atopic diseases allergic rhinitis serum IgE levels

Studysummary Abrocitinib effectively treats severe alopecia areata with significant improvement and no side effects.

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research European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata

4 citations , January 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

This consensus statement outlines a treatment algorithm for alopecia areata, detailing systemic treatment indications and options, including EMA-approved medications baricitinib and ritlecitinib for severe cases, as well as other off-label treatments and adjuvant therapies like oral minoxidil.

research A Case of Atopic Dermatitis with Alopecia Universalis in a Patient Treated with Abrocitinib

11 citations , February 2022 in “JAAD case reports”

This case report observed hair regrowth following the treatment of alopecia universalis and atopic dermatitis with tofacitinib, a JAK inhibitor.

Diffuse Alopecia Areata Is Associated With Intense Inflammatory Infiltration and CD8+ T Cells in Hair Loss Regions and an Increase in Serum IgE Level

research Diffuse Alopecia Areata Is Associated With Intense Inflammatory Infiltration and CD8+ T Cells in Hair Loss Regions and an Increase in Serum IgE Level

24 citations , January 2012 in “Indian Journal of Dermatology, Venereology and Leprology”

This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.