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Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Zinc is effective for treating various skin conditions, including warts and acne.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Estrogen therapy can reduce skin aging but has cancer risks.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.