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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Different types of skin cells play specific roles in development, healing, and cancer.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Wnt ligands are crucial for hair growth and repair.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Blocking JAK-STAT signaling can lead to hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.