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Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

VDR regulation varies by tissue and is crucial for its biological functions.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.

Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

No link found between aromatase gene and female hair loss.