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    Did you mean Estrogen Receptor Antagonist?
    Glossary Estrogen Receptor Antagonist

    blocks estrogen from activating its cellular receptors

    An Estrogen Receptor Antagonist, also known as an Estrogen Blocker or ER Antagonist, is a substance that binds to estrogen receptors on cells and prevents estrogen from exerting its effects. This can be useful in treating conditions like hormone-sensitive cancers, such as certain types of breast cancer, by inhibiting the growth-promoting effects of estrogen on these cancer cells.

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    Research 30 of 1000+

    1. Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 17 citations
    2. Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth Journal of Investigative Dermatology · 2016 · 8 citations
    3. Pantolactams as androgen receptor antagonists for the topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2011 · 5 citations
    4. Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo Skin Pharmacology and Physiology · 2019 · 1 citations
    5. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    6. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    7. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    8. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    9. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    10. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    11. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    12. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    13. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    14. Novel Dual Soft Drug Strategy Enables Development of Topical Androgen Receptor Antagonists with Enhanced Efficacy and Optimized Safety for Androgenetic Alopecia Journal of Medicinal Chemistry · 2026
    15. Androgen Receptor Ligands: Agonists and Antagonists Elsevier eBooks · 2017 · 2 citations
    16. Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships Current Medicinal Chemistry · 2000 · 204 citations
    17. Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a μ-opiate receptor agonist Pain · 1996 · 80 citations
    18. Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes Bioorganic & medicinal chemistry · 2005 · 45 citations
    19. Treatment of female pattern hair loss with the androgen receptor antagonist flutamide Australasian Journal of Dermatology · 2011 · 30 citations
    20. CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice PloS one · 2011 · 29 citations
    21. (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 14 citations
    22. Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium(III) chloride: Synthesis of 17α-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist Tetrahedron Letters · 1994 · 14 citations
    23. Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery Journal of Medicinal Chemistry · 2010 · 11 citations
    24. Oestrogen receptor antagonist and hair regrowth in dogs with hair cycle arrest (alopecia X) Veterinary dermatology · 2007 · 11 citations
    25. 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2009 · 11 citations
    26. Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 11 citations
    27. On the Effect of Estrogen Receptor Agonists and Antagonists on the Mouse Hair Follicle Cycle Journal of Investigative Dermatology · 1998 · 11 citations
    28. Association between Mineralocorticoid Receptor Antagonist and Mortality in SARS-CoV-2 Patients: A Systematic Review and Meta-Analysis Healthcare · 2022 · 10 citations
    29. Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist Expert opinion on pharmacotherapy · 2021 · 9 citations
    30. CRH receptor antagonists from <i>Pulsatilla chinensis</i> prevent CRH‐induced premature catagen transition in human hair follicles Journal of Cosmetic Dermatology · 2020 · 9 citations