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Humans lost body hair relatively recently in evolution.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Finasteride effectively blocks enzyme causing male pattern baldness.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Testosterone's muscle-building effects do not require its conversion to DHT.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.