research Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
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research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor
Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
research The Lanceolate Hair Rat Phenotype Results from a Missense Mutation in a Calcium Coordinating Site of the Desmoglein 4 Gene
A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
research Cultured Human and Rat Tooth Papilla Cells Induce Hair Follicle Regeneration and Fiber Growth
Tooth papilla cells can help regenerate hair follicles and grow hair.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Androgen Receptor in Rat Liver: Characterization and Separation from a Male-Specific Estrogen-Binding Protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Interaction of Spironolactone with Rat Skin Androgen Receptor
Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
research Microimaging of Hairless Rat Skin by Magnetic Resonance at 900 MHz
MRI can effectively image skin structures noninvasively.
research Effect of Inositol on Rat Alopecia
Inositol helped prevent and cure hair loss in rats.
research Effects of Dihydrotestosterone on Rat Dermal Papilla Cells In Vitro
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
DA-9401 helps protect rat testis from finasteride damage.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research The Preventive Effect of Vitamin D3 on Radiation-Induced Hair Toxicity in a Rat Model
Vitamin D3 may protect rat hair follicles from radiation damage.
research NFIC Promotes the Vitality and Osteogenic Differentiation of Rat Dental Follicle Cells
NFIC helps rat dental cells grow and turn into bone-like cells.
research Long-Term Preservation of Rat Skin Tissue by Epigallocatechin-3-O-Gallate
Green tea component EGCG helps keep rat skin grafts viable longer.
research The Effect of Topical Minoxidil Pretreatment on Nonsurgical Delay of Rat Cutaneous Flaps: Further Studies
Minoxidil improved rat skin flap survival but was less effective than surgical methods.
research Involucrin, But Not Filaggrin and Kdap mRNA, Expression Is Downregulated in 3-D Cultures of Intact Rat Hair Bulbs After Calcium Stimulation
Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.
research Protective Effect of Melatonin on Oxidative Stress Inducing Hair Follicle Injury in Scalded Rats
Melatonin may protect rat hair follicles from damage caused by oxidative stress after a burn.
research Nitric Oxide-Dependent Vasodilation Induced by Minoxidil in Isolated Rat Aorta
Minoxidil relaxes rat blood vessels mainly through nitric oxide and potassium channels.
research Chloroquine and Cinchonine Affect Rat Vascular Smooth Muscle Tonus Through Calcium Channels – In Silico and In Vitro Approaches
Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.
research The Effect of Finasteride on the Male Rat Brain
Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
research Sexually Dimorphic Effect of Progesterone and Its Reduced Metabolites on the Gene Expression of Myelin Proteins in Rat Schwann Cells
Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research Studies on Neurosteroids XXV: Influence of a 5α-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism
Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles
Minoxidil works in liver and outer hair root sheath for hair growth.
research Sensory Innervation of the Hairs of the Rat Hindlimb: A Light Microscopic Analysis
Different types of hairs on a rat's hindlimb have varying levels and patterns of nerve innervation.
research Distribution of P2X3-Immunoreactive Fibers in Hairy and Glabrous Skin of the Rat
P2X3-IR fibers are widespread in rat skin and likely help detect pain.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.