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Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Laser device increases hair density, safe for treating hair loss in men and women.

Finasteride safely lowers DHT levels without affecting testosterone.

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Aging causes skin stem cells to work less effectively.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Different types of stem cells and their environments are key to skin repair and maintenance.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.

Probiotic bacteria improved skin and hair health in aged mice.

Minoxidil shortens baldness from chemotherapy by 50.2 days without significant side effects.

The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.