71 citations
,
May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that trichothiodystrophy hair brittleness is linked to abnormalities in sulfur content and structural organization, making it prone to breakage.
20 citations
,
September 2018 in “Bioengineering & Translational Medicine” This review discusses regenerative medicine and explores the potential of molecular imaging in enhancing personalized therapies, but it reports no new research results.
16 citations
,
January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics” This study presents computational modeling and experimental analysis of the HGT protein KAP8.1, identifying key structural features that may influence hair's response to environmental conditions.
990 citations
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October 1999 in “Development” This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.
555 citations
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July 2001 in “Genes & Development” This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.
136 citations
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March 1996 in “Journal of the American Chemical Society” This study explains finasteride's high potency and specificity as a mechanism-based inhibitor for treating benign prostatic hyperplasia by detailing its interaction with human type 2 steroid 5α-reductase.
66 citations
,
June 2018 in “British Journal of Dermatology” These guidelines review the management of complications and specific forms of congenital ichthyosis and report no new results; they summarize expert and evidence-based recommendations for clinicians.
18 citations
,
January 2015 in “International Journal of Trichology” This study found that intralesional steroid treatment led to significantly more hair regrowth in alopecia areata patients than narrow band ultraviolet B therapy, while their combination did not enhance effectiveness.
16 citations
,
February 2016 in “Gynecological Endocrinology” This study observed two distinct phenotypes among North Indian women with PCOS: obese hyperinsulinaemic dysglycemic women from Delhi and lean hyperandrogenic women from Srinagar, despite being in the same region.
9 citations
,
July 2018 in “Journal of Testing and Evaluation” This study found that human hair fibers significantly improve the shear behavior of dry sand, but under saturated conditions, the reinforcement sustains shear strength similar to unreinforced sand.
5 citations
,
January 2021 in “PeerJ” This study observed that high levels of immunoreactive cortisol in the tail hair of captive Asian elephants were often associated with stressful or distinct behavioral events, suggesting its potential for reconstructing their physiological history.
2 citations
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December 2022 in “PNAS nexus” In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.
1 citations
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June 2022 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This article discusses the high risk and stress associated with medical malpractice lawsuits against plastic surgeons, particularly in cosmetic procedures, but provides no new research results.
1 citations
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April 2022 in “JAAD case reports” In this case report, researchers observed that a 47-year-old woman developed pityriasis amiantacea after using topical minoxidil, suggesting a potential new etiology for this scalp condition.
1 citations
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June 2021 in “International journal of pharmaceutical compounding” This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
1 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that hypothyroidism in women with PCOS significantly increased insulin resistance and obesity, which might worsen metabolic issues and impact conditions like hair loss and infertility.
1 citations
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January 2015 in “Der pharmacia lettre” This study found that neurosteroids might play a role in the neuroprotective effects of ischemic postconditioning by reducing brain infarct size and improving motor performance and memory in mice.
This chapter discusses how nanotechnology, through the use of metal nanoparticles and biocompatible carriers, along with antioxidants like curcumin, quercetin, and resveratrol, offers promising approaches for treating PCOS by reducing oxidative stress and inflammation, enhancing insulin sensitivity, and normalizing hormone levels.
October 2021 in “International journal of basic and clinical pharmacology” This case report discusses how trichomegaly, an adverse effect of the cancer therapy drug erlotinib, might serve as a marker of positive tumor response and potentially aid in treating madarosis.
January 2023 in “International Journal of Contemporary Pediatrics” This case study describes a 5-year-old boy with vitamin D dependent rickets type 2, motor delays, and alopecia totalis who showed improved biochemical parameters with calcium and calcitriol treatment.
August 2026 in “Recent Advances in Inflammation & Allergy Drug Discovery” This review discusses various factors influencing alopecia areata and explores newer therapeutic options like biologics and regenerative techniques, but it reports no new clinical trial results.
January 2026 in “Journal of Ayurveda and Integrated Medical Sciences” In this case study, a 20-year-old female with hypothyroidism experienced marked symptom improvement, including weight reduction and menstrual regularization, after Ayurvedic management involving herbal remedies and lifestyle changes, suggesting Ayurveda could complement conventional therapies and indicating the need for larger-scale validation.
May 2024 in “Microbial Biosystems Journal” This study found that the antifungal potential of six herbal shampoos developed using various phytoconstituents is comparable to marketed synthetic antifungal shampoos in treating Seborrheic dermatitis caused by Candida albicans.
December 2023 in “Azerbaijan Pharmaceutical and Pharmacotherapy J” This study formulated a minoxidil-loaded submicron emulsion-based topical gel, which demonstrated effective in vitro release, ex vivo permeation, and stability, suggesting it may offer a targeted treatment approach for alopecia compared to traditional methods.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
August 2023 in “International journal of experimental research and review” This study found that in models of diabetic wound healing, extracts from the flavonoid and tannin fractions of Ficus racemosa leaves improved wound closure time, increased breaking strength of incision wounds, and exhibited hypoglycemic activity.
This case report details a 38-year-old woman in Sri Lanka diagnosed with systemic lupus erythematosus-associated protein-losing enteropathy, identified through hypoalbuminemia and EULAR criteria in a resource-limited setting.
May 2022 in “International Journal of Health Sciences (IJHS)” This review discusses the diverse medicinal uses and pharmacological aspects of Hibiscus Rosa Sinensis Linn and highlights the need for further research on this plant.
November 2020 in “Dermatologic Therapy” January 2000 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report describes a middle-aged woman diagnosed with black piedra of the scalp, confirmed by potassium hydroxide examination and fungal culture.