This study found that 5% Adenophora Radix extract stimulated more hair follicles and shafts in a mouse model, suggesting potential as a hair loss prevention cosmetic.
This study found significant cephalometric changes in patients with skeletal Class III malocclusion treated with rapid maxillary expansion and reverse traction, demonstrating maxilla advancement and improved facial convexity.
This study details the presence of two types of cysts in rhino mouse skin, with utricles derived from hair canals and deeper cysts from hair root sheath epithelium.
1 citations
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November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in mice, knockout of Rac1 and Rac3 in keratinocytes led to reduced white adipose tissue and revealed Rac-dependent paracrine pathways affecting pre-adipocyte differentiation.
91 citations
,
July 2004 in “Journal of Biological Chemistry” This study found that overexpression of the enzyme SSAT in a mouse model significantly reduced prostate tumor size and progression, suggesting it could be a promising strategy against prostate cancer.
2 citations
,
March 2025 in “PNAS Nexus” In this study, researchers used Raman spectroscopy to identify melanin-specific features in mouse hair as potential biomarkers for gamma-radiation exposure, achieving a sensitivity of 88% and specificity of 83%, with classification accuracy declining over time beyond 7 days post-irradiation.
34 citations
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January 2016 in “Analytical Chemistry” This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.
December 2024 in “CONICET Digital (CONICET)” This study found that the small signaling peptide RALF22 plays a key role in root hair growth response to volatile compounds emitted by Penicillium aurantiogriseum through ethylene, auxin, and photosynthesis signaling in Arabidopsis.
15 citations
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December 2014 in “PLoS ONE” This study identifies iRhom2 as a crucial regulator of hair follicle differentiation, showing that the iRhom2Uncv mutation leads to dysplasia and reduced TACE maturation, resulting in a hairless phenotype in mice.
5 citations
,
December 2023 in “Current Biology” A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.
30 citations
,
May 2019 in “Scientific Reports” This study found enhanced remyelination in the corpus callosum of late pregnant rats compared to virgin and postpartum rats, suggesting a pregnancy-associated promyelinating effect mediated, in part, by the GABA A receptor system.
7 citations
,
September 1991 in “Journal of Andrology” In this study, 4‐MAPC treatment reduced ventral prostate weight in rats primarily through decreased synthetic activity, with testosterone propionate increasing prostate weight and activity at pharmacologic doses.
January 1999 in “Journal of the European Academy of Dermatology and Venereology” RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
9 citations
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December 2023 in “Materials Today Bio” This study found that modified microcrystalline cellulose with citric and ascorbic acid demonstrated enhanced hemostatic properties and biocompatibility in vitro and in animal hemorrhage models.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that rhamnose can restore hair-inducing gene expression in dermal papilla cells and accelerate hair follicle regeneration by promoting the hair cycle into the anagen phase, suggesting its potential therapeutic application for alopecia treatment.
3 citations
,
September 1989 in “Journal of Investigative Dermatology” This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.
25 citations
,
November 2010 in “Journal of Molecular Structure” This preliminary study suggests that Raman micro-spectroscopy can help differentiate basal cell carcinoma from hair follicles in skin tissue sections, although some misclassification of hair follicles as carcinoma was observed.
4 citations
,
July 2012 in “Linguistic Annotation Workshop” This study found that greater root surface area due to root hairs contributed to better growth and zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil.
1 citations
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April 2022 in “Crystal Growth & Design” 3 citations
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July 2022 in “Brain and Behavior” This study observed that a CARASIL mouse model demonstrated abnormal behavior, vascular and cellular changes, and upregulation of the TGF-β/Smad signaling pathway, indicating its potential involvement in CARASIL pathogenesis.
27 citations
,
November 2012 in “Journal of Biomedical Optics” This study used confocal Raman microscopy to confirm optical similarity between human and porcine hair follicles, supporting its use in assessing trans-follicular drug delivery.
10 citations
,
August 1998 in “Journal of Investigative Dermatology” This study observed that the compound EM-402 reduced 5α-reductase activity and sebaceous gland size in the flank organs and ears of hamsters, indicating potent localized anti-androgenic effects without systemic action.
5 citations
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March 2019 in “Journal of lipid research” This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.
4 citations
,
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study presents an improved reference genome for the African spiny mouse, which may aid in understanding its tissue regeneration at the molecular level.
1 citations
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November 2023 in “Pathogens” This study detected sarcoptic mange in five free-ranging raccoon dogs in Schleswig-Holstein, Germany, with four showing severe skin lesions and potential secondary bacterial infections, suggesting they may act as vectors in disease spread.
6 citations
,
March 1976 in “Journal of Investigative Dermatology” 14 citations
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March 2022 in “Plant Cell & Environment” In this study, the authors reported that AtRXR3, a phosphorus-inducible DUF506 protein, modulates root hair growth under phosphorus stress by interacting with calmodulin and influencing calcium oscillations.
1 citations
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February 2014 in “Archiv Der Pharmazie” This study demonstrated that steroidal carbamates 7–10 altered mRNA expression related to lipid metabolism in hamster flank organs and inhibited 5α-reductase activity without binding to the progesterone receptor.
9 citations
,
January 2014 in “Molecular Genetics and Metabolism Reports” This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.
July 1991 in “Endocrinology” This study suggests that combining the 5α-reductase inhibitor 4-MA with the antiandrogen Flutamide may improve prostate cancer therapy by additively inhibiting prostatic growth and androgen-sensitive functions in rats.