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Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair loss in men is common, treatable, but not curable.

Use minoxidil for hair loss treatment; assess results after 6 months.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Treat pattern hair loss with finasteride and topical minoxidil.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Use antiandrogens and other treatments for hair loss.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

Some skin diseases and their treatments can negatively affect male fertility.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Gender identity can be more diverse than just male or female.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.

Darker skin in 10-year-old girls may be an early sign of puberty.