research Menstrual Disorders in Adolescents
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
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900-930 / 1000+ results research Hair Follicle Transcriptome Analysis Reveals Genes Regulating Wool Fiber Diameter in Angora Rabbits
Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.
research Genome Scan for Signatures of Adaptive Evolution in Wild African Goat (Capra Nubiana)
Wild African goats have genetic adaptations for surviving harsh desert conditions.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Case Report: Reversal of Long-Standing Refractory Diffuse Non-Scarring Alopecia Due to Systemic Lupus Erythematosus Following Treatment With Tofacitinib
A patient with lupus and long-term hair loss saw significant hair regrowth after using the drug tofacitinib.
research Toxicity of Repeated Oral Intake of Organic Selenium, Inorganic Selenium, and Selenium Nanoparticles: A Review
Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
research Zinc and the Skin
Zinc is vital for skin health and overall body functions, and deficiency can cause serious health issues.
research The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test in CCHCR1-Deficient Mice
Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.
research Targeting Smoothened for Therapeutic Gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy
Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
research The Role of Leptin in Selected Skin Diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages
Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?
Studying rare genetic disorders can help us understand and treat common diseases better.
research FGF7-Dependent Inhibition of Human Hair Growth by an Osteopontin-Derived Peptide: A Novel Solution for Hirsutism and Hypertrichosis
A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.
research Dermal Wnt/β-Catenin Activation Tunably Controls Hair Follicle Initiation
Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
research Alopecia Universalis After Sitagliptin Intake
A patient's hair loss may be linked to their diabetes medication, Sitagliptin.
research Premature Hair Whitening Is an Independent Predictor of Carotid Intima-Media Thickness in Young and Middle-Aged Men
Early hair whitening may indicate a higher risk of heart disease in young and middle-aged men.
research Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?
Low iron and vitamin D levels are linked to hair loss in women.
research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research The De Novo DNA Methyltransferase DNMT3A Is Required for Epidermal Homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research 17β-Estradiol May Control Human Hair Follicle Growth Also via Up-Regulating the Expression of Cannabinoid Receptor Type 1
17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.
research Somatic Outcomes and Nutritional Management of Anorexia Nervosa
Early and precise nutritional intervention is crucial for managing anorexia nervosa.
research Comparison of Postoperative Mid-Term and Long-Term Quality of Life Between Billroth-I Gastroduodenostomy and Billroth-II Gastrojejunostomy After Radical Distal Gastrectomy in Patients With Gastric Cancer: A Cohort Study Based on a Case Registry Database
Both Billroth-I and Billroth-II methods have similar impacts on quality of life after gastric cancer surgery.
research HtrA1L364P Leads to Cognitive Dysfunction and Vascular Destruction Through TGF-β/Smad Signaling Pathway in CARASIL Model Mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
research Tebentafusp-Tebn (Kimmtrak®) for HLA-A*02:01-Positive Unresectable or Metastatic Uveal Melanoma
Tebentafusp-tebn improves survival rates in uveal melanoma patients but has common side effects like rash and fatigue.
research The Roles of Autophagy and Apoptosis in Burn Wound Progression in Rats
Treatments for burn wounds in rats should be timed according to whether autophagy or apoptosis is more active at certain times after the burn.
research An Incompletely Penetrant Novel MAFB (p.Ser56Phe) Variant in Autosomal Dominant Multicentric Carpotarsal Osteolysis Syndrome
Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.
research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways
LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
research Targeted Therapy in Melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.