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Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Wnt ligands are crucial for hair growth and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Estrogen therapy can reduce skin aging but has cancer risks.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Lowering testosterone speeds up wound healing in male mice.