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The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.

2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Using a single PSA level to decide on a prostate biopsy is not effective; a more personalized approach considering various factors is recommended.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Deoxyshikonin helps wounds heal faster in diabetic mice.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Patients with metabolic syndrome had lower Gleason scores when diagnosed with prostate cancer.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

New treatments are making advanced prostate cancer management more complex but also more hopeful.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

A new compound was made that might help treat diseases related to male hormones.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

Male pattern baldness may predict prostate cancer risk.