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Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Short daily photoperiods improve cashmere production in Inner Mongolia white cashmere goats.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Finasteride in male rats causes liver and metabolic issues in their offspring.

The mutation helps mice handle heat better without affecting hair growth.

Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.

Effective acne treatments should reduce sebum, bacteria, and inflammation, with isotretinoin being the best for severe cases.

High levels of prolactin in the blood can be linked to widespread hair loss.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.