research Exploring Hormone Therapy Effects on Reproduction and Health in Transgender Individuals
Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
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research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing
PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
research Cross-Sex Hormone Therapy for Gender Dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling, and Reverts Pathologic Gene Expression After Myocardial Infarction in Mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Applications of Steroid Drugs Entrapped in Cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Female Type of Adult Acne: Physiological and Psychological Considerations and Management
Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research The Cycle Characteristics and Outcomes of Infertile Nonclassic 21-Hydroxylase Deficiency Patients Undergoing Ovarian Stimulation for In Vitro Fertilization
Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.
research Transgender and Migraine: Impact of Hormone Therapy
Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Hereditary, Congenital, and Acquired Alopecias
Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.
research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Comprehensive Overview of Hidradenitis Suppurativa
The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.
research Diagnosis and Management of Polycystic Ovary Syndrome (PCOS)
The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.
research Safety of Testosterone Treatment in Postmenopausal Women
Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Treatment of Female Sexual Dysfunction in Postmenopausal Women: What Is the Evidence?
Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.
research Evaluation and Treatment of Gender Dysphoria to Prepare for Gender Confirmation Surgery
The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
research Skin Diseases in Horses
Horse skin diseases are complex to manage and often require a biopsy for accurate diagnosis and treatment.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis
The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
research Hereditary, Congenital, And Acquired Alopecias
Alopecia in animals can be hereditary, congenital, or acquired, with treatments and outcomes varying widely.
research Chemical Pharmacotherapy Options for Managing Adult Acne
The conclusion is that more research is needed to better understand and treat adult acne, and that patient education and simple treatment plans are important for better results.