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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Treatment during development affects hormone balance and sexual behavior in male rats.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

New drugs are improving treatment for hormone-related diseases in small pets.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.

Finasteride improves heart function and repairs damage after heart attack in mice.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

The conclusion is that more research is needed to better understand and treat adult acne, and that patient education and simple treatment plans are important for better results.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

PCOS is a long-term condition that needs more research for better understanding and treatment.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

Horse skin diseases are complex to manage and often require a biopsy for accurate diagnosis and treatment.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.