research Regenerative Surgery in the Management of Leg Ulcers
Using a patient's own tissue for micro-grafts may effectively treat non-healing leg ulcers and relieve pain.
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900-930 / 1000+ results research Stimulation of Mouse Hair Regrowth by Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells
Exosomes from human stem cells can help regrow hair in mice.
research Early and Late Matrix Progenitors Form the Terminally Differentiated Cell Layers of the Hair Follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Inhibition of Septin 4 (SEPT4; ARTS) for Wound Healing and Hair Follicle Regeneration: In Vitro and Mouse Studies
Blocking SEPT4 might help heal wounds and regrow hair faster.
research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research The Blastema and Epimorphic Regeneration in Mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research Prodrugs of Butyric Acid from Bench to Bedside: Synthetic Design, Mechanisms of Action, and Clinical Applications
New butyric acid prodrugs show promise for cancer treatment, anemia management, and protecting hair from chemotherapy damage.
research Scarring, Stem Cells, Scaffolds, and Skin Repair
Current skin repair methods for severe burns are inadequate, but stem cells and new materials show promise for better healing.
research Stem Cell Secretome as a New Booster for Regenerative Medicine
Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
research Wnt/β-Catenin Signaling Pathway Activates Melanocyte Stem Cells In Vitro and In Vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research An Ovol2-Zeb1 Transcriptional Circuit Regulates Epithelial Directional Migration and Proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in Various Pelage Hair Follicle Types
NF-κB is crucial for different stages and types of hair growth in mice.
research Stem Cell Competition for Niche Occupancy: Emerging Themes and Mechanisms
Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
research Lower Proximal Cup Cells But Not Bulge Stem Cells Regenerate Hair Follicles After Chemotherapy Injury
Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research The Role of MEK and Antizyme in Keratinocyte Stem Cell Expansion and Differentiation
Antizyme reduces tumor growth and normalizes skin cell development affected by MEK.
research Cellular and Molecular Characterization of Sebaceous Gland Self-Renewal and Regeneration Following Complete Genetic Ablation
The research found that a protein called PPARg is important for the formation and healing of sebaceous glands, which can regenerate independently from hair follicles.
research Induction Of Tissue-Specific Premature Stem Cell Aging Promotes Senescence-Like Phenotypes In Remote Multiple Organs
Aging in one type of stem cell can cause aging-like changes in various organs.
research Mesenchymal Stem Cells and Cell-Free Preparations for Treating Atopic Dermatitis
Mesenchymal stem cells and their secretions might help treat chronic skin inflammation in atopic dermatitis.
research EZH2 Is Required for Human Hair Follicle Growth and Epidermal Differentiation
EZH2 is essential for hair growth and skin cell development.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research The Effects of Sodium Metasilicate on Spinal Motoneuron Recovery Following Sciatic Nerve Injury
Sodium metasilicate improved spinal motoneuron recovery after sciatic nerve injury in rats.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research MicroRNA-205 Promotes Hair Regeneration by Modulating Mechanical Properties of Hair Follicle Stem Cells
MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
research Bone-Forming Cells with Pronounced Spread into the Third Dimension in Polymer Scaffolds Fabricated by Two-Photon Polymerization
Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research The Extracellular Matrix Dictates Regional Competence for Tumor Initiation
The extracellular matrix affects where tumors can start in the body.