2 citations
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May 2017 in “InTech eBooks” This review discusses the regenerative potential of hair follicle stem cell populations and current approaches to reconstructing folliculogenesis for alopecia therapy, but reports no new clinical results.
October 2023 in “Frontiers in medicine” Targeted immunotherapy could be a promising new treatment for hair regrowth.
12 citations
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July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
117 citations
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November 2006 in “Experimental Dermatology” This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.
70 citations
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February 2015 in “Expert Opinion on Drug Discovery” This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
14 citations
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October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.
April 2003 in “Experimental Dermatology” This workshop review from the Australian Hair and Wool Research Society discusses findings in cutaneous biology and endocrinology but presents no new research results.
February 2026 in “Frontiers in Pharmacology” This review suggests a shift toward genetically informed treatments for male pattern hair loss by integrating genetic insights and pharmacogenetic markers into therapeutic decision-making.
November 2025 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this case report, researchers describe a 44-year-old woman with refractory patch alopecia areata achieving complete hair regrowth using a multi-modal approach of systemic and topical cholecalciferol with microneedling, although systemic vitamin D repletion remains a significant confounder.
6 citations
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May 2013 in “PloS one” This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.
11 citations
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August 2018 in “Asian-Australasian journal of animal sciences” This study found that a short daily photoperiod increased crude protein digestibility, secondary hair follicle activity, and cashmere quality in Inner Mongolia white cashmere goats without harming fiber characteristics.
April 2026 in “International Journal of Molecular Sciences” In this study, Ageratum houstonianum ethanolic extract and its active component agerarin were found to promote hair growth and follicle elongation by increasing SCUBE3 expression via activation of MAPK–AP-1 signaling in human dermal papilla cells, suggesting potential therapeutic value for treating hair loss.
July 2025 in “International Journal of Trichology” This review investigates how various intrinsic factors—such as growth factors, cytokines, chemokines, and interferons—regulate hair growth through evidence gathered from in vitro and in vivo studies, highlighting the need for further research in human subjects to validate these findings.
95 citations
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March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
December 2025 in “Advanced Healthcare Materials” In this study, a new topical formulation containing amine-activated carboxymethyl chitosan and hydrolyzed extracellular matrix showed promising results in a mouse model by reducing oxidative stress, inflammation, and promoting hair regeneration, potentially offering an alternative treatment for inflammatory hair loss.
October 2024 in “Cosmetics” This review highlights the lack of research on Afro-textured hair, emphasizing the need for better understanding of its genetic traits and molecular structure to develop more effective hair care solutions.
This study reviewed existing literature to demonstrate that thyroid disorders have a significant and underestimated impact on hair loss, highlighting gaps in current knowledge and the need for further research to better diagnose and manage hair disorders linked to thyroid dysfunction.
In this network meta-analysis, the researchers reported that topical minoxidil 5% was the most effective off-label therapy for increasing hair density in men with androgenetic alopecia, while other treatments like melatonin and cetirizine showed potential benefits, highlighting a need for further comparative trials.
26 citations
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February 2022 in “Journal of pineal research” This review examines melatonin's potential effects on human skin and hair follicle pigmentation, highlighting the need to confirm findings from cell cultures in physiological tissue contexts.
March 2026 in “Cosmetics” In this comprehensive review, researchers reported that macromolecules like type I collagen, keratin, and ceramides enhance hair health by improving follicular function and increasing hair density, strength, shine, and resilience, as shown in various in vitro, animal, and human studies.
June 2026 in “Journal of Dermatological Science” This study found that a topical formulation containing DMG-Na significantly improved hair loss parameters in people experiencing hair loss, suggesting its potential effectiveness for such conditions.
48 citations
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September 1993 in “The journal of experimental zoology/Journal of experimental zoology” In this study, melatonin implants advanced and synchronized spring hair growth in goats by initiating fiber growth earlier than in untreated goats, with associated suppression of normal prolactin rise.
7 citations
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June 2015 in “The anatomical record” This study in Hexi cashmere goats found that secondary follicle activity increases with time, and Hoxc13 expression varies significantly across different growth stages, suggesting a role in follicle activity.
107 citations
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September 2002 in “Journal of Investigative Dermatology” This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.
90 citations
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January 2002 in “Dermatology” This study describes the kenogen phase, where hair follicles rest after shedding, and finds its duration and frequency are greater in individuals with androgenetic alopecia, potentially contributing to baldness.
January 2007 in “Durham e-Theses (Durham University)” This document details the usage policy for full-text reproduction from Durham E-Theses, providing guidelines for personal, educational, and non-commercial purposes without altering the text.
40 citations
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December 2004 in “Dermatology” This study suggests that an increase in kenogen phases, along with rising vellus hair cycles and fewer normal hair cycles, is associated with the progression of female androgenetic alopecia.
136 citations
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June 2006 in “Journal of Dermatological Science” This study found that injecting PDGF-AA and -BB into mouse skin immediately triggered the hair growth cycle's anagen phase, suggesting potential treatment options for certain types of alopecia.