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research Lichen planus pigmentosus (LPP) and lichen planus pigmentosus: 35 cases in Armenia, Colombia
Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.
research Parry–Romberg Syndrome: Radioclinical Dissociation in a Paucisymptomatic Form and a Proposed Diagnostic Framework
In this case report, a 38-year-old woman with Parry–Romberg syndrome displayed left-sided facial atrophy and subclinical central nervous system involvement detectable by neuroimaging, suggesting that even symptom-free cases may benefit from systematic brain evaluations.
research Segregation of Incomplete Achromatopsia and Alopecia Due to PDE6H and LPAR6 Variants in a Consanguineous Family from Pakistan
This study identified specific genetic variants as the cause of visual impairment and non-syndromic alopecia in two brothers, reinforcing the link between PDE6H variants and achromatopsia and LPAR6 variants and alopecia.
research Epimorphic regeneration in mice is p53-independent
This study reports that in MRL mice, loss of p53 does not impair ear regeneration, suggesting p21's potential role in this process may involve the Tgfb/Smad pathway.
research Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled
This study found that RXRα/RARγ heterodimers are necessary for retinoic acid-induced keratinocyte proliferation in the skin, while normal epidermal maintenance does not require RAR-mediated signaling.
research Safety of Platelet‐Rich Plasma Subepithelial Infusion for Vocal Fold Scar, Sulcus, and Atrophy
This study found that platelet-rich plasma injections for vocal fold scarring and atrophy showed a favorable safety profile and subjective improvements in vocal quality and fatigue over a three-month follow-up.
research 1369 Terminalia chebula fruit extract from PSR™ technology demonstrates strong anti-aging and antioxidant properties
This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.
research Comprehensive Analysis of Platelet-Rich Plasma for the Treatment of Female Pattern Hair Loss: A Subgroup-Based Review of Clinical Evidence
This study suggests that platelet-rich plasma may provide short-term improvement in hair density for female pattern hair loss, but results varied and more rigorous trials are needed to establish optimal protocols.
research Predominance of CD27-PD-1- Effector Memory T Cells Re-Expressing CD45RA Characterizes Treatment-Resistant Severe Alopecia Areata
CD8+ T cells re-expressing CD45RA may predict treatment resistance in severe alopecia areata.
research Intradermal injection of platelet-rich plasma for periorbital wrinkles: A review
This narrative review reported that intradermal injection of autologous platelet-rich plasma showed objective improvement and increased patient satisfaction in treating periorbital wrinkles, though the authors noted the need for further rigorous studies to confirm these findings.
research PLATELET RICH PLASMA THERAPY FOR SKIN REJUVENATION
This article discusses the use of Platelet Rich Plasma therapy for skin rejuvenation and hair loss and reports no new clinical results, noting its minimally invasive nature and effect on skin texture and elasticity.
research Effectiveness of low-level laser therapy in lichen planopilaris
This study found that low-level laser therapy may reduce inflammation and increase hair thickness in patients with lichen planopilaris after six months of treatment, though the small sample size limits the findings.
research Surgical Management of Severe Cicatricial Ectropion Secondary to Pityriasis Rubra Pilaris.
This article reviews multiple noncutaneous manifestations of pityriasis rubra pilaris, such as subungual hyperkeratosis and hair loss, but reports no new clinical results.
research 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia
This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.
research Prevalence of hormonal and endocrine dysfunction in patients with lichen planopilaris (LPP): A retrospective data analysis of 168 patients
This study found that postmenopausal women with lichen planopilaris showed a high prevalence of androgen excess, while women with frontal fibrosing alopecia were often associated with androgen deficiency.
research Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes
This study identified that Eda-A1 unexpectedly induces placode inhibitors dkk4 and lrp4, indicating the importance of tightly regulated signaling for proper ectodermal organ development.
research Expression analysis of proteasome maturation protein (POMP) gene in Liaoning Cashmere goat
This study observed that POMP is strongly expressed in the root sheath hair follicles of Liaoning Cashmere goats and its expression can be regulated by certain factors, which may influence cashmere growth.
research 854 CCL5 affects the hair-inductive capacity of three-dimensional (3D)-cultured dermal papilla cells
This study suggests that alkaline phosphatase-regulated expression of CCL5 contributes to the trichogenicity of human dermal papilla spheres.
research Variables affecting the potential efficacy of platelet-rich plasma in dermatology
This article discusses the therapeutic use of platelet-rich plasma (PRP) in dermatology, specifically its challenges and potential in treating conditions like lichen planopilaris, but reports no new findings.
research 422 Human hair follicles express PD-L1, whose expression is down-regulated by EGFR and MEK inhibitors ex vivo. A potential mechanism for EGFR inhibitor induced sterile folliculitis
This study found that epidermal growth factor receptor and mitogen activated protein kinase inhibitors down-regulate PD-L1 expression in human hair follicles, which may contribute to sterile folliculitis in treated patients.
research Platelet Rich Plasma stimulates human hair growth in vitro
This study found that Platelet-Rich Plasma (PRP) stimulated human hair growth more effectively than other tested culture media in vitro.
research IPL sources and ruby lasers for hair reduction - trying to compare apples and oranges
Choose IPL for versatility and speed, ruby lasers for precision.
research Platelet Rich Plasma and Its Use in Hair Regrowth: A Review
This review examines the definition, classification, mechanism, clinical efficacy for hair regrowth, and potential adverse effects of platelet rich plasma, but does not present new experimental results.
research Lichen Planopilaris: The first biopsy layer microbiota inspection
This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.
research A Hero Revealed: Targeting the AHR for treatment of inflammatory skin diseases
This study investigated AHR signaling's role in skin biology and reported that novel AHR ligands may help restore keratinocyte function and reduce inflammation in skin diseases, suggesting their potential as therapeutic agents.
research Platelet-rich plasma
This study found that platelet-rich plasma may be an effective adjuvant treatment for androgenetic alopecia, especially when combined with antiandrogenetic medications and topical minoxidil, though factors like patient age and family history could influence outcomes.
research The Use of Platelet-Rich Plasma in Aesthetic and Regenerative Medicine: A Comprehensive Review
This review discusses various aesthetic and regenerative applications of platelet-rich plasma and concludes that it has potential as a safe cosmetic intervention but requires further studies to understand its clinical effects.
research Serum Level of Programmed Death Ligand1 in Alopecia Areata Patients in Relation to Disease Severity
This study found that programmed death-ligand 1 (PD-L1) levels correlated with the severity of alopecia areata, suggesting its potential as an indicator and possible target for new treatments.
research The use of platelet-rich plasma in dermatology
This article reviews the regenerative benefits of platelet-rich plasma in various medical fields, particularly in dermatology and aesthetic medicine, without presenting new clinical data.