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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Fungi-produced compounds can change plant root growth.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Stem cell niches support, regulate, and coordinate stem cell functions.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Turing patterns are now recognized as important in developmental biology.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.