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Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Men with testicular cancer were less likely to experience baldness and severe acne.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Mutations in certain receptors can cause diseases and offer new treatment options.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The new classification system for skin disorders emphasizes the importance of understanding a patient's awareness of their condition for better treatment.

Researchers identified specific genes that are important for mouse skin cell development and healing.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

Small molecule IM boosts hair growth by changing stem cell metabolism.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

Hair in mammals likely evolved from glandular structures, not scales.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.