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Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Understanding fetal skin development helps diagnose congenital skin diseases.

Excess androgens may cause PCOS, not just be a symptom.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Adrenal disorders can cause lasting brain and behavior issues in children.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

A male with aromatase deficiency improved bone health with estradiol treatment.