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Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Aging alone rarely causes significant hair loss; hormones are a bigger factor.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Estrogen therapy helped regrow hair in a bald man.

A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.

Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

SGK3 is essential for proper hair growth and health.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

A rare skin disorder, Ichthyosis with confetti, has no cure but treatment focuses on managing symptoms with moisturizers.

A newborn with congenital syphilis had unusual hair loss possibly caused by the infection.

Bald men may have a lower risk of testicular cancer.

The girl with autoimmune hair loss might regrow hair within a year, and treatments can help but not prevent recurrence; dermatologist referral and corticosteroids are recommended.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.