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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Dandruff is a common, winter-worsened scalp condition linked to inflammation and microorganisms, treatable with products like ketoconazole, and may affect hair loss.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Sunlight worsens hair loss; protect scalp.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Using both vertical and transverse sections gives a better diagnosis of alopecia than using one method alone.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Bimatoprost, a glaucoma medication, may also help treat hair loss.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.