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This review discusses hormone replacement therapy for menopausal women, emphasizing DHEA's unique ability to convert into sex steroids only in targeted tissues, and reports no new clinical results.

This article discusses the role of androgens in metabolic and reproductive health and reports no new experimental results; the focus is on androgen receptor activation by testosterone and 5α-dihydrotestosterone.

This study found that despite the presence of steroidogenesis inhibitors, CRPC tumor cells adapt to continue synthesizing androgens, suggesting a need for more effective androgen axis targeting.

This study found that the androgen precursors DHEA and androstenedione stimulated androgen-sensitive parameters in the sebaceous glands of the skin in castrated male hamsters.

This study concludes that in men, telogen effluvium (TE) precedes androgenetic alopecia (AGA), with anagen shortening occurring before follicle miniaturization.

This study found that women with female pattern baldness had a marked increase in the 3α,17β-androstanediol glucuronide/sex hormone binding globulin ratio and low serum sex hormone binding globulin.

This study found no association between circulating androgens and prostate cancer risk, underscoring the complex role of androgen metabolism in the prostate.

This study suggests that human skin locally synthesizes active sex steroid hormones, impacting inflammation, cell behavior, and wound healing, with potential implications for therapies in aging and impaired wound recovery.

The authors concluded that plasma levels of 3α-diolG, ADTG, and DHTG in women with hyperandrogenic disorders primarily reflect adrenal androgen contributions rather than peripheral action, suggesting a potential index for treatment effectiveness.

This case report presents a rare instance of an ovarian steroid cell tumor in a 68-year-old female with virilism, which normalized androgen levels following surgical removal.

This study found that in rheumatoid arthritis patients, inflammatory macrophages activate steroid metabolism to increase glucocorticoid and androgen production, which helps suppress inflammation and attenuate hyperproliferation in synovial fibroblasts, with notable disturbances seen in postmenopausal women due to diminished inactive steroid precursors.

Early hair loss may indicate risk of insulin resistance.

This study found that male pattern hair loss may be associated with differences in serum levels of androstenedione, cortisol, 17 beta-estradiol, and luteinizing hormone, compared to controls.

This study reported that administering finasteride reduced levels of certain neuroactive androgens in rat brains, suggesting peripheral origin for most 3α,5α-Adiol and brain synthesis for 3α,5α-A.

This study observed that in cases of moderately severe male-pattern hirsutism, elevated free plasma androgen levels occur in 85% of patients, suggesting a subtle hyperandrogenic state as a common underlying factor.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

This study found that caucasian subjects had higher serum levels of 5 alpha-reduced androgen metabolites compared to Chinese subjects, suggesting racial differences in 5 alpha-reductase activity and a potential mechanism for increased body hair in caucasian men.

This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.

This review discusses the current understanding of androgen biosynthesis, mechanisms of action, and their roles in human biology, as well as related congenital and acquired disorders, but it reports no new research findings.

This article reviews the unapproved use of testosterone for treating female androgen insufficiency and reports no new clinical results.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.

This review discusses the development and potential therapeutic applications of steroid sulfatase inhibitors for hormone-dependent disorders and cognitive dysfunction, reporting no new clinical results.

This article reviews congenital adrenal hyperplasia, a group of rare genetic disorders affecting steroid synthesis, and highlights the need for specific therapy and ongoing monitoring, but reports no new clinical findings.

This article reviews the impact of diet on acne, suggesting that dairy and high-glycemic foods may contribute to acne development, but it presents no new clinical findings.

This review highlights the increasing association of metabolic syndrome with various dermatological conditions and suggests a link through chronic inflammation, oxidative stress, and endocrine abnormalities, yet reports no new findings.

This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.

This study describes the development of a polyherbal hair growth serum using rosemary and fenugreek extracts, which demonstrated stable physicochemical properties, suggesting its potential as a cosmeceutical product for managing hair loss and promoting scalp health.

This study describes developing a polyherbal hair growth serum with rosemary and fenugreek extracts, which met physicochemical standards and may serve as a stable and compatible option for managing hair loss and promoting scalp health.

This article discusses the complexities of diagnosing and managing polycystic ovary syndrome in adolescents and highlights the lack of established diagnostic criteria and unclear clinical implications, without presenting new clinical findings.