April 2019 in “Journal of Investigative Dermatology” Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
130 citations,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
119 citations,
June 2021 in “Heliyon” Licorice has many health benefits but should be used carefully due to possible side effects.
40 citations,
November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
25 citations,
June 2022 in “Developmental cell” Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
15 citations,
February 2021 in “Frontiers in immunology” Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
10 citations,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
9 citations,
December 2022 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.
6 citations,
December 2022 in “Frontiers in Pharmacology” Quercetin may help improve symptoms of polycystic ovary syndrome.
4 citations,
November 2022 in “Frontiers in Immunology” Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
2 citations,
January 2023 in “Journal of Clinical Medicine” People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.
1 citations,
March 2023 in “Phytochemistry Reviews” CBD may improve skin and hair health, but its effective use and safety need more research.
1 citations,
January 2023 in “International Journal of Molecular Sciences” Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
January 2017 in “Indian journal of drugs in dermatology” Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.
March 2012 in “Hair transplant forum international” Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
238 citations,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
2 citations,
April 2017 in “Actas Dermo-Sifiliográficas” Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.
4 citations,
January 2019 in “Therapeutic Advances in Endocrinology and Metabolism” Medications for PCOS don't seem to raise heart disease risk.
April 2024 in “Journal of clinical medicine” Effective treatment guidelines for frontal fibrosing alopecia are still unclear.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
12 citations,
January 2010 in “Pediatric Health” Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
1 citations,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
April 2024 in “Canadian Women s Health Today” PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.
September 2023 in “Journal of Cosmetic Dermatology” Finasteride was more effective than hydroxychloroquine in treating frontal fibrosing alopecia.
8 citations,
July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
144 citations,
December 2017 in “Pigment cell & melanoma research” Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
29 citations,
June 2020 in “International Journal of Molecular Sciences” Notch signaling disruptions can cause various skin diseases.