Glycogen helps E. coli cells divide unevenly and organize their contents.
7 citations
,
August 2017 in “European journal of endocrinology” This study suggests that mutations in exon 10 of the POC1A gene may be linked to a distinct clinical condition characterized by extreme insulin resistance and short stature, differing from SOFT syndrome.
August 2026 in “Diabetes Metabolic Syndrome and Obesity” This review explores the complex, context-specific roles of Wnt/β-catenin signaling in six diabetic complications and suggests that targeted modulation could improve both pathological and functional outcomes.
January 2015 in “DSpace@MIT (Massachusetts Institute of Technology)” This study found that overexpression of the metabolic enzyme PHGDH can promote cancer initiation and progression, highlighting its significant role in tumor cell proliferation and tumorigenesis.
18 citations
,
July 2019 in “Clinical Endocrinology” The researchers reported that among Mediterranean Sicilian women with PCOS, Phenotype B exhibited the most severe metabolic abnormalities, notably obesity and altered glucose metabolism, whereas Phenotype D showed no such issues.
January 2017 in “Diabetes case reports” This review discusses the importance of early diagnosis and a multidisciplinary approach in managing polycystic ovary syndrome to prevent metabolic complications and address dermatological issues.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting the Mitochondrial Pyruvate Carrier in human hair follicles ex vivo activated the integrated stress response, affecting cell proliferation and metabolism.
35 citations
,
January 2024 in “BioMolecular Concepts” This review discusses the relationship between oxidative stress and polycystic ovarian syndrome and reports no new clinical results; the authors emphasize the need for further research into therapeutic strategies.
257 citations
,
July 2018 in “Obstetrics & Gynecology” This review discusses the various phenotypes and diagnostic challenges of polycystic ovary syndrome, highlighting its complex pathophysiology and associated health risks, and reports no new clinical results.
December 2015 in “Vascular Pharmacology” Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
76 citations
,
May 2011 in “Liver transplantation” The authors concluded that liver transplantation in children with propionic acidemia can reduce the risk of metabolic decompensation and enhance quality of life, although some metabolic issues may persist.
68 citations
,
January 2022 in “International Journal of Molecular Sciences” This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.
2 citations
,
January 2021 in “Journal of Cosmetics, Dermatological Sciences and Applications” In this study, phenol-enriched olive mill wastewater extract positively influenced hair growth in vitro by promoting human dermal papilla cell proliferation, increasing insulin-like growth factor-1 secretion, and reducing reactive oxygen species, suggesting it may be beneficial for hair care.
11 citations
,
June 1979 in “British Journal of Dermatology” This study found that the dehydroepiandrosterone hydroxylating enzyme system in hair follicles is similar to the liver monooxygenase system, sharing characteristics such as inhibition by carbon monoxide and dependency on NADPH.
1 citations
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December 2015 in “Endocrinology” This study suggests that dietary decanoic acid may manage hyperandrogenism and insulin resistance in PCOS, as observed in animal and cell model experiments.
July 2025 in “Journal of Pharmacognosy and Phytochemistry” This review explores the potential benefits of plant-based diets, herbal remedies, and phytochemicals for managing PCOS, suggesting they may help regulate menstrual cycles, improve metabolic parameters, and reduce androgen levels, offering a promising, holistic approach to treatment.
7 citations
,
March 2011 in “Hormone and Metabolic Research” This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.
December 2024 in “Frontiers in Genetics” This review discusses the genetic causes and pathogenesis of Olmsted syndrome, emphasizing the potential for a genotype-phenotype correlation due to TRPV3 mutations, and explores avenues for individualized treatment developments for this condition.
6 citations
,
May 2022 in “Journal of Organometallic Chemistry” This study developed a catalytic system using indenyl-molybdenum(II)-bipyridine complexes and ionic liquid solvents to achieve a 95% yield of campholenic aldehyde from α-pinene oxide under mild conditions.
60 citations
,
June 1997 in “Baillière's clinical obstetrics and gynaecology” This article reviews the potential mechanisms underlying polycystic ovary syndrome, emphasizing insulin resistance and hormone dysregulation, and reports no new research findings.
April 2026 in “Amino Acids” This study reviews prior research using transgenic K6/ODC mice and demonstrates that elevated polyamines in epithelial cells contribute significantly to skin tumor development and progression by stimulating proliferation, altering cell signaling and chromatin remodeling, and affecting immune functionality, amongst other mechanisms.
October 2010 in “Reproductive Biomedicine Online” This study reported that MALDI-TOF Mass Spectrometry profiling demonstrated nearly 100% sensitivity and specificity in detecting adenomyosis and leiomyoma, revealing potential peptide markers for these conditions.
May 2025 in “Nutrition and Diabetes” This study found that elevated 1-hour plasma glucose in women with PCOS was associated with increased risk of metabolic disorders and gestational diabetes, indicating it may be a useful marker for adverse metabolic status.
May 2026 in “International Journal of Molecular Sciences” This study suggests that hydroxytyrosol may influence inflammation and oxidative stress pathways in androgenetic alopecia, particularly through interaction with the PTGS2 gene, warranting further experimental validation.
12 citations
,
January 2022 in “International Journal of Clinical Practice” This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.
3 citations
,
December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
1 citations
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May 2011 in “Molecular Medicine Reports” This study found no association between the -866G/A polymorphism in the UCP2 gene and the development of polycystic ovary syndrome.
February 2024 in “Advanced Materials” In this study, researchers discovered that a newly identified oligosaccharide, OG6, promotes hair growth by activating hair follicles, achieved by revealing its hidden activity from a larger molecule structure.
10 citations
,
January 2011 in “Skin research and technology” This study found that procyanidin oligomers bind to keratin and inhibit oxidative hair damage, suggesting their potential use in protective hair care products.
1 citations
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June 2023 in “Reproduction” This review discusses the role of microglia in mediating prenatal androgen effects on the female brain, potentially contributing to PCOS development and neuroendocrine dysfunctions, but reports no new results.