90 citations,
August 2002 in “European journal of endocrinology” Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.
9 citations,
December 1987 in “European journal of endocrinology” The treatment significantly reduced hair growth and male hormone levels in hirsute women.
December 2024 in “International Journal of Advanced Research” Metformin and vitamin D3 help manage insulin resistance and hormonal imbalances in obese PCOS patients.
32 citations,
February 2017 in “Human Reproduction” Women with polycystic ovary syndrome tend to have a longer anogenital distance.
12 citations,
March 2017 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.
989 citations,
August 2007 in “The Lancet” PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
155 citations,
March 2006 in “The American Journal of Medicine” Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
5 citations,
January 2020 in “Research journal of pharmacy and technology” CBD may help reduce stress and pain in women with PCOS.
September 2002 in “Fertility and sterility” Female relatives of PCOS patients have a higher chance of showing PCOS symptoms.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.
11 citations,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
January 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Norethisterone (jenapharm) therapy is effective for endometrial cancer.
11 citations,
November 2002 in “Dermatologic Surgery” IPL can cause unexpected hair growth in nearby untreated areas.
21 citations,
January 2003 in “Seminars in reproductive medicine” The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
11 citations,
November 2017 in “Hong Kong Medical Journal” Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
March 2024 in “Journal of Neuroscience Research” Finasteride may reduce depression and anxiety in female rats and improve brain connectivity.
3 citations,
March 2018 in “Journal of Continuing Education in Nursing” Continuing education programs significantly increased rural nurse practitioners' knowledge about PCOS.
10 citations,
February 2017 in “Hormone Molecular Biology and Clinical Investigation” Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
192 citations,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
April 2017 in “European Psychiatry” Some antidepressants can cause emotional numbness and other unusual side effects.
35 citations,
June 1997 in “Annals of the New York Academy of Sciences” Early diagnosis and multidisciplinary care are crucial for managing PCOS in adolescents.
20 citations,
March 2017 in “Reproductive Biology and Endocrinology” Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
21 citations,
January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Acne is an important sign of androgen excess disorders in women.
19 citations,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
June 2008 in “CRC Press eBooks” PCOS may have evolved as an advantage in past environments with food scarcity.
1 citations,
January 2017 in “Journal of rare disease research & treatment” Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
4 citations,
August 2021 in “Clinical and Experimental Reproductive Medicine” The 2018 guideline for PCOS suggests new diagnostic criteria and treatments, but recognizes the need for more research.
26 citations,
January 2016 in “Indian journal of endocrinology and metabolism” Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.
6 citations,
January 2012 in “Indian Journal of Endocrinology and Metabolism” Old drugs are often used for new, different medical purposes in endocrine pharmacology.
17 citations,
June 2010 in “Journal of Cosmetic Dermatology” Many women with hard-to-treat acne also have PCOS.