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      Lifestyle Changes in Women with Polycystic Ovary Syndrome

      research Lifestyle changes in women with polycystic ovary syndrome

      198 citations , July 2011 in “Cochrane library”
      This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.
      Prevalence of Male and Female Pattern Hair Loss in Maryborough

      research Prevalence of Male and Female Pattern Hair Loss in Maryborough

      193 citations , August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”
      This study found that the prevalence of androgenetic alopecia increases with age among both men and women in Maryborough, Australia, with 57% of women and 73.5% of men aged 80 and over affected.
      Biology of Estrogens in Skin: Implications for Skin Aging

      research Biology of estrogens in skin: implications for skin aging

      187 citations , December 2005 in “Experimental Dermatology”
      This article discusses the role of estrogens in skin aging and reports no new findings; it highlights the potential of selective ER modulators to improve skin health without systemic side effects.
      Alopecia Areata: Treatment Options and Efficacy

      research Alopecia areata

      182 citations , December 2017 in “Journal of the American Academy of Dermatology”
      This article reviews current and emerging treatments for alopecia areata, including Janus kinase inhibitors, highlighting variability in clinical outcomes and the lack of sustained remission.
      The PDGF/PDGFR Pathway as a Drug Target

      research The PDGF/PDGFR pathway as a drug target

      182 citations , November 2017 in “Molecular Aspects of Medicine”
      This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.
      Skin Aging and Menopause: Implications for Treatment

      research Skin Aging and Menopause

      180 citations , January 2003 in “American Journal of Clinical Dermatology”
      This article reviews the effects of menopause on skin aging and suggests that hormone replacement therapy may help reverse some of these changes.
      Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      178 citations , August 2016 in “Advances in wound care”
      This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
      Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing

      research Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing

      176 citations , August 2015 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.
      Why Some Women Look Young for Their Age

      research Why Some Women Look Young for Their Age

      175 citations , November 2009 in “PLOS ONE”
      This study found that both genetic and environmental factors influence appearance-related aging in women, with skin wrinkling, hair graying, and sun damage significantly affecting perceived age more than chronological age.
      A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control

      research A Hot New Twist to Hair Biology

      174 citations , April 2005 in “˜The œAmerican journal of pathology (Print)”
      This study found that TRPV1 activation in human scalp hair follicles inhibited hair shaft elongation, suppressed proliferation, and induced apoptosis, suggesting TRPV1 as a potential target for managing hair growth and epithelial disorders.
      Fetal Alcohol Syndrome: Current Status of Pathogenesis

      research Fetal Alcohol Syndrome: Current Status of Pathogenesis

      171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”
      The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
      Wound Healing and the Use of Medicinal Plants

      research Wound Healing and the Use of Medicinal Plants

      170 citations , September 2019 in “Evidence-based Complementary and Alternative Medicine”
      This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
      Hirsutism and Acne in Polycystic Ovary Syndrome

      research Hirsutism and acne in polycystic ovary syndrome

      169 citations , August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology”
      This article discusses treatments for hirsutism and acne in women with polycystic ovary syndrome, suggesting that lower doses of current medications maintain efficacy while reducing cost and side effects, but reports no new clinical results.
      Anthracycline Analogs: The Past, Present, And Future

      research Anthracycline analogs The past, present, and future

      168 citations , December 1986 in “Cancer Chemotherapy and Pharmacology”
      Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
      Zinc Therapy in Dermatology: A Review

      research Zinc Therapy in Dermatology: A Review

      165 citations , January 2014 in “Dermatology Research and Practice”
      This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
      Low-Level Laser Therapy for Treatment of Hair Loss

      research Low‐level laser (light) therapy (LLLT) for treatment of hair loss

      165 citations , August 2013 in “Lasers in Surgery and Medicine”
      This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
      Interventions for Alopecia Areata

      research Interventions for alopecia areata

      164 citations , April 2008 in “Cochrane library”
      This review of interventions for alopecia areata found no significant treatment benefits for hair growth compared to placebo, indicating a need for larger, well-conducted studies.
      Metabolic Risk in PCOS: Phenotype and Adiposity Impact

      research Metabolic risk in PCOS: phenotype and adiposity impact

      162 citations , January 2015 in “Trends in Endocrinology and Metabolism”
      This review discusses how women with PCOS have an increased risk of insulin resistance and cardiometabolic features regardless of body fat, and calls for targeted prevention and management strategies.
      Probing the Effects of Stress Mediators on the Human Hair Follicle

      research Probing the Effects of Stress Mediators on the Human Hair Follicle

      159 citations , November 2007 in “American Journal of Pathology”
      In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.